Human Campylobacter IgG Lateral flow dipstick kit 6272
kit
Assay type Sandwich assay, lateral flow (dipstick)
Research area Infectious Disease
Sample type Serum, plasma, whole blood
Components
10X Wash Buffer
100 mL
TMB Substrate
40 mL
Milk Powder
5 g
Instructions for Use
1 Each
Evaluation Form
1 Each
Test Strips
2 kits of [2 Vials x 10 Each]
Anti-Human IgG Conjugate
500 µL
Positive Control
140 µL
Negative Control
140 µL
Storage Store at 2-8°C.
Additional information
Mikrogen recomLine Campylobacter tests are serological, qualitative in vitro tests for the
detection of IgG and IgA antibodies against immunodominant antigens of Campylobacter jejuni
and Campylobacter coli. After going through a Campylobacter infection or in case of a
persistent infection which is primarily detected through stool culture, our recomLine Campylobacter
tests with separately lined up recombinantly produced antigens allow the determination of specific
antibodies for the clarification of post-infectious complications (e.g., Campylobacter-induced arthritis).
Advantages
Separate detection of IgG and IgA antibodies.
Simple and clear interpretation due to easy-to-read banding.
Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.
Highest sensitivity and specificity through use of recombinant, immunodominant antigens:
Bands
Description
Antigen
Molecular Weight [kDa]
Major outer membrane protein (porA)
MOMP
46
Cell-binding factor 2 (cbf2)
PEB4
31
Major antigenic peptide PEB2
PEB2
27
Major cell-binding factor (cbf1)
PEB1
28
Peptidoglycan-associated lipoprotein
OMP18
18
Putative ATP/GTP binding protein
P39
39
target relevance
human antibody anti-Campylobacter
Campylobacter
Description Bacterial genus that causes campylobacteriosis and gastrointestinal infections
Structure Campylobacter is a genus of Gram-negative, microaerophilic, spiral-shaped or curved rod bacteria belonging to the family Campylobacteraceae. Members of the genus are highly motile due to the presence of polar flagella, which enable corkscrew-like movement through mucus and host tissues. The most clinically significant species are Campylobacter jejuni and Campylobacter coli, which are among the leading causes of bacterial gastroenteritis worldwide. Campylobacter species commonly colonize the intestinal tracts of poultry, cattle, and other animals and are transmitted to humans primarily through contaminated food, water, or direct animal contact. The bacteria possess numerous virulence factors that facilitate adherence to and invasion of intestinal epithelial cells, resulting in inflammation and tissue damage.
Diagnosis The diagnosis of Campylobacter infection is performed through microbiological, molecular, and antigen detection methods. Isolation of the organism from stool specimens using selective culture media under microaerophilic conditions remains a standard diagnostic approach. Molecular methods such as polymerase chain reaction (PCR) provide rapid and highly sensitive detection of Campylobacter DNA and are increasingly incorporated into multiplex gastrointestinal pathogen panels. Antigen detection assays may also be used in some clinical laboratories. Laboratory confirmation is important because the symptoms of campylobacteriosis overlap with those caused by numerous other bacterial, viral, and parasitic enteric pathogens.
Symptoms Campylobacter infection, known as campylobacteriosis, typically develops following an incubation period of approximately two to five days after exposure. Common symptoms include diarrhea, which may be bloody, abdominal pain, fever, nausea, vomiting, headache, and malaise. The abdominal pain may be severe and can mimic acute appendicitis. Most infections are self-limiting and resolve within one week; however, severe disease may occur in young children, elderly individuals, and immunocompromised patients. Rare but important complications include bacteremia, reactive arthritis, irritable bowel syndrome, and Guillain-Barré syndrome, an autoimmune neurological disorder that can result in muscle weakness and paralysis.
Data
FAQ & Publications
Frequently Asked Questions
What sample types are compatible with the Human Campylobacter IgG Lateral Flow Dipstick Kit 6272?
The kit is compatible with serum, plasma, and whole blood samples for the detection of Human Campylobacter IgG antibodies.
How should the Human Campylobacter IgG Lateral Flow Dipstick Kit 6272 be stored to maintain its stability?
The kit should be stored at 2-8°C to ensure optimal stability and performance.
Publications
pmid
title
authors
citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
relevant to this product
This product has moved to a digital protocol. Please use the URL provided on the product packaging to access the electronic Instructions for Use (eIFU). 6272 protocol
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