Name: Human Chlamydia IgA/IgM Lateral flow dipstick kit 6173
SKU: 6173
Availability: InStock

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Chlamydia IgA (IgM)
species reactivity	Chlamydia (C. pneumoniae, C. trachomatis, C. psittaci)
applications	Lateral flow (dipstick)
assay type	Indirect & qualitative
available sizes	20 test kits

Human Chlamydia IgA/IgM Lateral flow dipstick kit 6173

kit

Assay type
Sandwich assay, lateral flow (dipstick)

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

10X Wash Buffer	100 mL
TMB Substrate	40 mL
Milk Powder	5 g
Instructions for Use	1 Each
Evaluation Form	1 Each
Test Strips	2 kits of [2 Vials x 10 Each]
Anti-Human IgA Conjugate	500 µL
Positive Control	140 µL
Negative Control	140 µL

Storage
Store at 2-8°C.

Additional information

Mikrogen recomLine Chlamydia tests are serological, qualitative in vitro tests that allow the determination of the immune response of all three human pathogenic Chlamydia species in a single assay. They consist of different species-specific, recombinantly produced antigens on nitrocellulose strips that can be used to determine IgG, IgA, and IgM antibodies against immunodominant C. trachomatis, C. pneumoniae, and C. psittaci antigens.

The recomLine Chlamydia can be used as a confirmatory test but also as a screening test.

Advantages

Immune status of a possible C. trachomatis, C. pneumoniae, and C. psittaci infection can be confirmed in one preparation and on one strip.
Helpful for in vitro fertilization diagnostics due to the species-specific antigens MOMP, TARP, CPAF, and HSP60 of C. trachomatis.
Highly specific detection of C. pneumoniae due to the use of species-specific antigens, e.g., YwbM.
Only assay for specific serological C. psittaci diagnostics.
Can be used as both screening and confirmatory assay.
Separate detection of IgG, IgA, and IgM antibodies.
Simple and clear interpretation due to easy-to-read banding.
Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.
Highest sensitivity and specificity through use of recombinant, species-specific antigens:

Bands

Antigen	Species	Signification
MOMP	C. tr., C. pn., C. ps.	"major outer membrane protein"; Immunodominant outer membrane antigen
OMP2	C. tr., C. pn., C. ps.	"major outer membrane protein 2"; cysteine-rich outer membrane protein; general marker for infection with Chlamydia
TARP	C. tr., C. pn., C. ps.	"translocated actin-recruiting protein"; Binds actin
CPAF	C. tr., C. pn., C. ps.	"chlamydial protease-like activity factor"; Virulence factor
HSP60	C. tr.	"heat shock protein 60"; In

target relevance
Organism Chlamydia abortus
Protein names Chlamydia
Structure and strains Chlamydia abortus is a species in Chlamydiota that causes abortion and fetal death in mammals, including humans. Chlamydia abortus was renamed in 1999 as Chlamydophila psittaci along with all Chlamydiota except Chlamydia trachomatis. This was based on a lack of evident glycogen production and on resistance to the antibiotic sulfadiazine. In 1999 C. psittaci and C. abortus were recognized as distinct species based on differences of pathogenicity and DNA DNA hybridization. In 2015, this new name was reverted to Chlamydia
Detection and diagnosis Approximately two weeks after the first symptoms of a primary infection an increase of the IgA and IgM antibody activity occurs, which peaks after five weeks and usually declines by the 10th week. The IgG antibody activity reaches a maximum around week twelve and remains detectable for several years. In cases of reinfection IgA and IgG antibodies reappear rapidly.

Data

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.