Herpes simplex Virus 2 Glycoprotein G Antigen BA1052RVS-G

$1,054.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Herpes Simplex Virus (HSV) 2 Glycoprotein G Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA1052RVS-G Category: Infectious disease proteins Tags: antigen, Herpes simplex Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Herpes simplex Virus 2 Glycoprotein G
species reactivity	Herpes Simplex Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Herpes simplex Virus 2 Glycoprotein G Antigen BA1052RVS-G

kit
Research area Infectious Disease
Storage Store at -65°C. Avoid freeze/thaw cycles. Sonicate before use.
Form liquid
Associated products Herpes simplex Virus 2 Glycoprotein G Antigen (BA1052RVS-G) Herpes simplex Virus 2 Antigen (BA1052VS) Herpes Simplex Virus 2 gP IgG Control Serum (BC1052G) Herpes Simples Virus 2 IgM Control Serum (BC1052M) Herpes simplex Virus 2 IgG ELISA Kit (ESR1052G) Herpes simplex Virus 2 IgM ELISA Kit (ESR1052M)

target relevance
Herpes Simplex Virus (HSV)
Description Virus that causes oral herpes, genital herpes, and other mucocutaneous infections
Structure Herpes simplex viruses (HSV) are enveloped, double-stranded DNA viruses belonging to the genus Simplexvirus within the family Herpesviridae. Two closely related species, Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2), are responsible for the majority of human infections. The viral genome is enclosed within an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing glycoproteins that mediate attachment and entry into host cells. Following primary infection, HSV establishes lifelong latency within sensory neurons, particularly in the trigeminal and sacral ganglia. Periodic reactivation of latent virus results in recurrent infections and viral shedding, often in the absence of symptoms. HSV infections are widespread globally and represent some of the most common viral infections of humans.
Diagnosis The diagnosis of herpes simplex virus infection is performed through clinical evaluation and laboratory testing. Molecular methods such as polymerase chain reaction (PCR) are highly sensitive and specific and are considered the preferred diagnostic approach for detecting HSV DNA in lesion swabs, cerebrospinal fluid, and other clinical specimens. Viral culture may also be used, particularly for active lesions, although it is generally less sensitive than PCR. Direct fluorescent antibody testing and antigen detection assays may provide rapid identification in selected settings. Serological assays, including ELISA-based tests, can detect HSV-specific antibodies and help distinguish previous exposure to HSV-1 and HSV-2. Laboratory confirmation is particularly important in cases of neonatal herpes, encephalitis, and atypical presentations.
Symptoms Herpes simplex virus infections produce a wide range of clinical manifestations depending on the site of infection and immune status of the host. Primary infection may be asymptomatic or may present with painful vesicular lesions involving the oral cavity, lips, genital region, skin, or eyes. HSV-1 most commonly causes oral herpes characterized by fever, gingivostomatitis, and recurrent cold sores, whereas HSV-2 is more frequently associated with genital herpes causing painful ulcers, itching, dysuria, and regional lymphadenopathy. Recurrent episodes are typically milder than primary infections due to partial immune control. In immunocompromised individuals and neonates, HSV can cause severe disseminated disease. Rare but serious complications include herpes encephalitis, keratitis leading to vision loss, meningitis, and neonatal herpes, which may be life-threatening if untreated.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Herpes simplex Virus 2 Glycoprotein G Antigen BA1052RVS-G?

This antigen is primarily used for the detection of IgA, IgG, and IgM antibodies in ELISA assays, enabling the indirect and quantitative measurement of immune responses against HSV-2 glycoprotein G.

How should the Herpes simplex Virus 2 Glycoprotein G Antigen be stored to maintain its stability?

The antigen should be stored at -65°C and freeze/thaw cycles should be avoided to preserve its integrity. It is also recommended to sonicate the antigen before use.

Is the Herpes simplex Virus 2 Glycoprotein G Antigen compatible with serological assays for HSV-1 and HSV-2?

Yes, the antigen targets HSV-2 glycoprotein G and is suitable for serotype-specific detection of HSV-2 antibodies, which is important for distinguishing between HSV-1 and HSV-2 infections.

What is the form and amount provided for the Herpes simplex Virus 2 Glycoprotein G Antigen BA1052RVS-G?

The product is supplied as a liquid form and is available in a 1 mg quantity, with lot-specific concentration specified in mg/mL.

What species does the Herpes simplex Virus 2 Glycoprotein G Antigen BA1052RVS-G specifically react with?

This antigen is reactive with Herpes Simplex Virus species, specifically targeting the glycoprotein G of HSV-2.

What is the primary application for the Herpes simplex Virus 1 Glycoprotein G Antigen BA1051RVS-G?

This antigen is suitable for detecting IgA, IgG, and IgM antibodies against Herpes simplex Virus 1 glycoprotein G in ELISA assays, providing indirect and quantitative analysis.

How should the Herpes simplex Virus 1 Glycoprotein G Antigen be stored to maintain its stability?

The antigen should be stored at -65°C and should be protected from freeze/thaw cycles to preserve its integrity. It is recommended to sonicate the solution before use.

Is this antigen specific to any species, and which virus does it target?

The antigen targets Herpes simplex Virus 1 glycoprotein G and is reactive with Herpes Simplex Virus species.

What is the format and concentration information available for this Herpes simplex Virus 1 antigen product?

The product is provided in a liquid form with a lot-specific concentration specified in mg/mL, and the available size is 1 mg per vial.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.