t Measles Virus IgG ELISA Kit ESR102G – benchmark antibodies
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Measles Virus IgG ELISA Kit ESR102G - Image 2

Measles Virus IgG ELISA Kit ESR102G

$334.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Measles Virus IgG ELISA Kit
  • Suitable for IgG detection
  • Ready-to-use
  • 96 tests
SKU: ESR102G Category: Tags: ,
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Human Measles Virus reactive IgG

species reactivity

Measles Virus

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Measles Virus IgG ELISA Kit ESR102G
kit
Target name
Human Measles Virus IgG
Assay type
Indirect ELISA
Overview
The SERION ELISA classic Masern/Measles Virus IgG and IgM tests are quantitative and qualitative immunoassays for the detection of human antibodies in serum or plasma directed against Measles Virus. The SERION ELISA classic Masern/Measles Virus IgM test is recommended for the determination of acute infections. The SERION ELISA classic Masern/Measles Virus IgG assay is recommended for determination of immune status and for detection of intrathecal synthesized IgG antibodies in cerebrospinal fluid for CSF diagnostics.
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Components
Break apart microtiter test strips each with antigen coated single wells8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgG-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
2-8°C
Associated products
Measles Antigen (BA102VS)
Measles Virus IgG Control Serum (BC102G)
Measles Virus IgM ELISA Kit (ESR102M)
Measles Virus IgM Control Serum (BC102M)
Measles Antigen [premium] (BA102VS-S)
Additional information
Additional Serion Kit Information
target relevance
Organism
Measles morbillivirus (MeV)
Structure and strains
The measles virus genome is typically 15,894???nucleotides long and encodes eight proteins. The WHO currently recognises 8 clades of measles (A???H). Subtypes are designed with numerals???A1, D2 etc. Currently, 23 subtypes are recognised. The 450 nucleotides that code for the C???terminal 150 amino acids of N are the minimum amount of sequence data required for genotyping a measles virus isolate.

Despite the variety of measles genotypes, there is only one measles serotype. Antibodies to measles bind to the hemagglutinin protein. Thus, antibodies against one genotype (such as the vaccine strain) protect against all other genotypes.

Disease
Measles Viruses occur worldwide and belong to the family of paramyxoviridae. The pathogen is transmitted by close contact with infected individuals primarily by droplet infection. Due to the high infectivity of the virus, measles is usually aquired during childhood.

After an incubation period of 10 to 12 days Koplik??s spots typically appear on oral mucosa in 60 to 70% of cases. In the course of the prodromal period flu-like symptoms may escalate until the typical measles exanthema arises with sharply increasing fever. The exanthema spreads from face to the extremities. The clinical symptoms peak within several days with a corresponding rapid recovery. Complications occur frequently, mainly pneumonia and encephalitis. Infection results in a life-long immunity. A combination of attenuated life vaccines for mumps, measles and rubella (MMR) has been available for several years.
Detection and diagnosis
Demonstration of IgM antibodies is commonly used as evidence for an acute infection and provides positive test results early on with the onset of symptoms. The demonstration of IgG antibodies serves primarily for immune status and vaccination control as well as for confirmation of Measles Virus infections. The detection of IgG antibodies in CSF samples is particularly recommended in cases of suspected encephalitis and multiple sclerosis.

Publications

pmidtitleauthorscitation
23114697Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of lifeReikie BA, Naidoo S, Ruck CE, Slogrove AL, de Beer C, la Grange H, Adams RC, Ho K, Smolen K, Speert DP, Cotton MF, Preiser W, Esser M, Kollmann TR.Clin Vaccine Immunol. 2013 Jan;20(1):33-8. doi: 10.1128/CVI.00557-12. Epub 2012 Oct 31.
23114697Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of lifeReikie BA, Naidoo S, Ruck CE, Slogrove AL, de Beer C, la Grange H, Adams RC, Ho K, Smolen K, Speert DP, Cotton MF, Preiser W, Esser M, Kollmann TR.Clin Vaccine Immunol. 2013 Jan;20(1):33-8. doi: 10.1128/CVI.00557-12. Epub 2012 Oct 31.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

relevant to this product
ESR102G protocol
#
EO0198Safety Data SheetQC certificate

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