Measles Virus IgG ELISA Kit Control serum BC102G

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Measles Virus IgG Control Serum
Applications: ELISA
IgG control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC102G Categories: control serum, Virion/Serion kits Tags: ELISA control serum, Measles Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Measles Virus reactive IgG Kit control
species reactivity	Measles Virus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Measles Virus IgG ELISA Kit Control serum BC102G

kit
Assay type Indirect ELISA
Overview Ready-to-use positive controls for the qualitative and quantitative antigen determination when using immunoassays of the SERION ELISA classic,SERION ELISA antigen and SERION ELISA agile product line in accordance with modern quality guidelines. In addition to the controls contained in the SERION ELISA test kit, the ready-to-use components are an additional, external reagent for checking the validity of the test run carried out, for determining the laboratory-internal error limits and for documenting the batch-to-batch consistency of the method used. As part of extensive validation studies, target values and areas of validity are determined for each test-specific SERION ELISA control and documented on batch-specific certificates of analysis. These serve as guide values, particularly within the framework of internal laboratory quality assurance in accredited testing laboratories in accordance with the guidelines of the German Medical Association (RiLiBAK).
Research area Infectious Disease
Sample type
Storage 2-8°C
Associated products Measles Antigen (BA102VS) Measles Virus IgG ELISA Kit (ESR102G) Measles Virus IgM ELISA Kit (ESR102M) Measles Virus IgM Control Serum (BC102M) Measles Antigen [premium] (BA102VS-S)
Additional information Additional Serion Kit Information

target relevance

human antibody anti-Measles Virus

Measles Virus

Description
Virus that causes measles (rubeola)

Structure
Measles virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Morbillivirus within the family Paramyxoviridae. Humans are the only known natural reservoir of the virus. The viral particle contains a lipid envelope with fusion (F) and hemagglutinin (H) glycoproteins that mediate attachment to and entry into host cells. Measles virus is one of the most contagious human pathogens known and is transmitted primarily through respiratory droplets and airborne aerosols. Following infection, the virus initially replicates in the respiratory tract and regional lymphoid tissues before disseminating systemically. Measles virus can induce transient but profound immune suppression, increasing susceptibility to secondary infections for weeks to months after recovery. Widespread vaccination has dramatically reduced disease incidence in many regions, although outbreaks continue to occur where vaccination coverage is insufficient.

Diagnosis
The diagnosis of measles virus infection is performed through serological and molecular methods. Detection of measles-specific IgM antibodies by ELISA is commonly used to confirm recent infection, while IgG antibody testing may be used to assess immune status or evidence of prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) provides highly sensitive detection of viral RNA in respiratory specimens, throat swabs, nasopharyngeal samples, urine, and blood and is particularly useful during the early phase of infection. Viral genotyping may be performed for epidemiological investigations and outbreak surveillance. Laboratory confirmation is important because clinical symptoms can resemble those of other viral exanthematous illnesses.

Symptoms
Measles virus infection typically develops following an incubation period of approximately seven to fourteen days. Early symptoms include high fever, cough, coryza (runny nose), conjunctivitis, malaise, and characteristic Koplik spots on the oral mucosa. Several days later, a maculopapular rash appears, beginning on the face and spreading downward to the trunk and extremities. Additional symptoms may include headache, fatigue, loss of appetite, and lymphadenopathy. Although most individuals recover completely, severe complications can occur, particularly in young children, malnourished individuals, pregnant women, and immunocompromised patients. Complications include otitis media, pneumonia, diarrhea, encephalitis, and the rare but fatal neurological disorder subacute sclerosing panencephalitis (SSPE). Measles remains a significant cause of vaccine-preventable morbidity and mortality worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Measles Virus IgG ELISA Kit Control serum BC102G?

The Measles Virus IgG ELISA Kit Control serum BC102G is designed for use as a positive control in ELISA assays, specifically for qualitative and quantitative antigen determination in SERION ELISA classic, antigen, and agile product lines.

How should the Measles Virus IgG ELISA Kit Control serum BC102G be stored to maintain its stability?

The control serum should be stored refrigerated at temperatures between 2-8°C to ensure stability and optimal performance.

Is the Measles Virus IgG ELISA Kit Control serum BC102G compatible with all measles virus ELISA kits?

This control serum is pre-diluted and ready-to-use specifically for SERION ELISA classic and SERION ELISA antigen assays, ensuring compatibility within these assay systems.

What type of antibody does the Measles Virus IgG ELISA Kit Control serum BC102G contain and what is its target?

The control serum contains human IgG antibodies reactive against the measles virus, targeting the measles virus antigen for indirect and quantitative ELISA detection.

How is the quality and consistency of the Measles Virus IgG ELISA Kit Control serum BC102G validated?

Each batch undergoes extensive validation studies with target values documented on batch-specific certificates of analysis, which serve as guide values for internal laboratory quality assurance following guidelines of the German Medical Association (RiLiBAK).

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC102G protocol

Documents

#
CP0070	Safety Data Sheet	QC certificate

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Measles Virus IgG ELISA Kit Control serum BC102G

Data

FAQ & Publications

Protocols

Documents

Reviews

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