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Measles Virus IgG ELISA Kit Control serum BC102G

$94.00

Summary

  • Virion/Serion Diagnostic Kit Control for research use (RUO)
  • Measles Virus IgG Control Serum
  • Applications: ELISA
  • IgG control serum
  • Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
  • 3 mL
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Human Measles Virus reactive IgG Kit control

species reactivity

Measles Virus

applications

ELISA

assay type

Indirect & quantitative

available size

3 mL

Available product – Measles Virus IgG ELISA Kit Control serum BC102G

kit
Target name
Human Measles Virus IgG
Assay type
Indirect ELISA
Overview
Ready-to-use positive controls for the qualitative and quantitative antigen determination when using immunoassays of the SERION ELISA classic,SERION ELISA antigen and SERION ELISA agile product line in accordance with modern quality guidelines.In addition to the controls contained in the SERION ELISA test kit, the ready-to-use components are an additional, external reagent for checking the validity of the test run carried out, for determining the laboratory-internal error limits and for documenting the batch-to-batch consistency of the method used.As part of extensive validation studies, target values ​​and areas of validity are determined for each test-specific SERION ELISA control and documented on batch-specific certificates of analysis. These serve as guide values, particularly within the framework of internal laboratory quality assurance in accredited testing laboratories in accordance with the guidelines of the German Medical Association (RiLiBÄK).
Research area
Infectious Disease
Storage
2-8°C
Associated products
Measles Antigen (BA102VS)
Measles Virus IgG ELISA Kit (ESR102G)
Measles Virus IgM ELISA Kit (ESR102M)
Measles Virus IgM Control Serum (BC102M)
Measles Antigen [premium] (BA102VS-S)
Additional information
Additional Serion Kit Information
target relevance
Organism
Measles morbillivirus (MeV)
Structure and strains
The measles virus genome is typically 15,894 nucleotides long and encodes eight proteins. The WHO currently recognises 8 clades of measles (A–H). Subtypes are designed with numerals—A1, D2 etc. Currently, 23 subtypes are recognised. The 450 nucleotides that code for the C‐terminal 150 amino acids of N are the minimum amount of sequence data required for genotyping a measles virus isolate.

Despite the variety of measles genotypes, there is only one measles serotype. Antibodies to measles bind to the hemagglutinin protein. Thus, antibodies against one genotype (such as the vaccine strain) protect against all other genotypes.

Disease
Measles Viruses occur worldwide and belong to the family of paramyxoviridae. The pathogen is transmitted by close contact with infected individuals primarily by droplet infection. Due to the high infectivity of the virus, measles is usually aquired during childhood.

After an incubation period of 10 to 12 days Koplik´s spots typically appear on oral mucosa in 60 to 70% of cases. In the course of the prodromal period flu-like symptoms may escalate until the typical measles exanthema arises with sharply increasing fever. The exanthema spreads from face to the extremities. The clinical symptoms peak within several days with a corresponding rapid recovery. Complications occur frequently, mainly pneumonia and encephalitis. Infection results in a life-long immunity. A combination of attenuated life vaccines for mumps, measles and rubella (MMR) has been available for several years.
Detection and diagnosis
Demonstration of IgM antibodies is commonly used as evidence for an acute infection and provides positive test results early on with the onset of symptoms. The demonstration of IgG antibodies serves primarily for immune status and vaccination control as well as for confirmation of Measles Virus infections. The detection of IgG antibodies in CSF samples is particularly recommended in cases of suspected encephalitis and multiple sclerosis.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
BC102G protocol

Documents

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