| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | IRAK2 |
| available sizes | 100 µg |
rabbit anti-IRAK2 polyclonal antibody 8028
$445.00
Antibody summary
- Rabbit polyclonal to IRAK2
- Suitable for: ELISA,WB,ICC,IF
- Isotype: IgG
- 100 µg
rabbit anti-IRAK2 polyclonal antibody 8028
| antibody |
|---|
| Tested applications WB,ICC/IF,ELISA |
| Recommended dilutions Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Whole cell lysate from HeLa cells or K562 cells. No cross- reactivity with IRAK. |
| Immunogen Peptide corresponding to aa 546- 564 of human IRAK2. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) |
| Gene names IRAK2,IRAK2 |
| Protein family Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily |
| Mass 69433Da |
| Function FUNCTION: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. {ECO:0000269|PubMed:10383454, ECO:0000269|PubMed:9374458}. |
| Tissues TISSUE SPECIFICITY: Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. {ECO:0000269|PubMed:9374458}. |
| Structure SUBUNIT: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1. {ECO:0000269|PubMed:9374458}. |
| Domain DOMAIN: The protein kinase domain is predicted to be catalytically inactive. |
| Target Relevance information above includes information from UniProt accession: O43187 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of IRAK2 in HeLa (H) and K562 (K) whole cell lysate with IRAK2 antibody (C2) at 2 µg/mL. |
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| Immunocytochemical staining of HeLa cells using IRAK2 antibody at 2 µg/mL. |
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| Immunofluorescence of IRAK-2 in Hela cells with IRAK-2 antibody at 10 µg/mL. |
 |
| Immunofluorescence of IRAK-M in human spleen tissue with IRAK M antibody at 20 µg/mL.
Green: IRAK-2 Antibody (8028) Blue: DAPI staining |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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