Skip to content

mouse anti-von Willebrand Factor monoclonal antibody (VW92-3) 5389

$497.00

Antibody summary

  • Mouse monoclonal to von Willebrand Factor
  • Suitable for: WB,IHC
  • Isotype: IgG2a
  • 200 µg
SKU: 5389parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG2a

clonality

monoclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

Human von Willebrand Factor

available sizes

200 µg

Available product – mouse anti-von Willebrand Factor monoclonal antibody (VW92-3) 5389

antibody
Tested applications
WB,IHC,IHC
Recommended dilutions
ELISA: 1-10ug/ml with vWF on the solid phase

Western Blot: 5-10ug/ml; useful under non-reducing conditions.

Immunohistochemistry: 5-10ug/ml on paraffin embedded and frozen tissue sections.
Immunogen
Human plasma von Willebrand Factor.
Size and concentration
200µg and
Form
lyophilized
Storage Instructions
The stock solution (2. 0mg/ml) can be stored in aliquots at - 20°C for 1 year or can be stored at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not
Storage buffer
PBS, 1% BSA, pH 7.4, lyophilized.
Purity
immunogen affinty purifcation
Clonality
monoclonal
Isotype
IgG2a
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monocolonal IgG2a - Isotype Control
target relevance
Protein names
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
Gene names
VWF,VWF F8VWF
Mass
309265Da
Function
FUNCTION: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Subellular location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10961880}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10961880}. Note=Localized to storage granules.
Tissues
TISSUE SPECIFICITY: Plasma.
Structure
SUBUNIT: Multimeric. Interacts with F8. {ECO:0000269|PubMed:10961880, ECO:0000269|PubMed:9218428}.
Post-translational modification
PTM: All cysteine residues are involved in intrachain or interchain disulfide bonds.; PTM: N- and O-glycosylated. {ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218}.
Target Relevance information above includes information from UniProt accession : P04275
The UniProt Consortium

Data

No results found

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC

Documents

#
No results found

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.