Immunohistochemistry (IHC) : Human placenta stained with anti-PLAP antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of trophoblasts..

mouse anti-PLAP monoclonal antibody (ZM161) 6337

$160.00 – $528.00

Antibody summary

Mouse monoclonal to PLAP
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG2b
Control: Placenta
Visualization: Membrane
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6337parent Category: antibody Tags: anatomy, Gynecological Pathology, PLAP

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG2b
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-PLAP monoclonal antibody ZM161 6337

antibody
Database link: human P05187
Tested applications IHC
Recommended dilutions As directed
Immunogen Recombinant full-length human ALPP protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG2b
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG2b - Isotype Control

target relevance
Protein names Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)
Gene names ALPP,ALPP PLAP
Protein family Alkaline phosphatase family
Mass 9606Da
Function Alkaline phosphatase that can hydrolyze various phosphate compounds.
Catalytic activity BINDING 64; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 64; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 114; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 177; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 238; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 291; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 292; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 307; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250\|UniProtKB:P05186"; BINDING 333; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 338; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 342; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 379; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 380; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"; BINDING 454; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269\|PubMed:11124260, ECO:0000269\|PubMed:15946677, ECO:0000269\|PubMed:16815919, ECO:0000269\|PubMed:20693656"
Subellular location Cell membrane; Lipid-anchor, GPI-anchor .
Tissues Detected in placenta (at protein level).
Structure Homodimer.
Target Relevance information above includes information from UniProt accession: P05187
The UniProt Consortium

Data

Human placenta stained with anti-PLAP antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of trophoblasts..

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.