Immunohistochemistry (IHC) : Human placenta stained with anti-PLAP antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of trophoblasts..

mouse anti-PLAP monoclonal antibody (ZM161) 6337

$160.00 – $528.00

Antibody summary

Mouse monoclonal to PLAP
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG2b
Control: Placenta
Visualization: Membrane
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6337parent Category: antibody Tags: anatomy, Gynecological Pathology, PLAP

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG2b
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-PLAP monoclonal antibody ZM161 6337
antibody
Database link:
human P05187
Tested applications
IHC
Recommended dilutions
Concentrated 1:50-100
Application Notes
Positive control: Placenta
Immunogen
Recombinant full-length human ALPP protein
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG2b
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monoclonal IgG2b - Isotype Control
target relevance
Protein names
Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)
Gene names
ALPP,ALPP PLAP
Protein family
Alkaline phosphatase family
Mass
9606Da
Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
Catalytic activity
BINDING 64; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 64; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 114; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 177; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 238; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250|UniProtKB:P05186"; BINDING 291; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250|UniProtKB:P05186"; BINDING 292; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250|UniProtKB:P05186"; BINDING 307; /ligand="Ca(2+)"; /ligand_id="ChEBI:CHEBI:29108"; /evidence="ECO:0000250|UniProtKB:P05186"; BINDING 333; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 338; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 342; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 379; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 380; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="1"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"; BINDING 454; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_label="2"; /evidence="ECO:0000269|PubMed:11124260, ECO:0000269|PubMed:15946677, ECO:0000269|PubMed:16815919, ECO:0000269|PubMed:20693656"
Subellular location
Cell membrane; Lipid-anchor, GPI-anchor .
Tissues
Detected in placenta (at protein level).
Structure
Homodimer.
Target Relevance information above includes information from UniProt accession: P05187
The UniProt Consortium

Data

Human placenta stained with anti-PLAP antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of trophoblasts..

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.