| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | P-Cadherin |
| available sizes | 100 µg |
mouse anti-Human P-cadherin monoclonal antibody (NCC-CAD-299) 8198
$484.00
Antibody summary
- Mouse monoclonal to Human P-cadherin
- Suitable for: WB,IHC,Inhibition
- Isotype: IgG1
- 100 µg
mouse anti-Human P-cadherin monoclonal antibody (NCC-CAD-299) 8198
| antibody |
|---|
| Tested applications WB,IHC,IHC |
| Recommended dilutions Western Blotting: 5-10 ug/ml, non-reducing and non-heating conditions. Immunohistochemistry: 5-10 ug/ml, frozen tissue sections. Cell Contact Inhibition Assays: 100 ug/ml |
| Immunogen Human epidermal carcinoma cell line A431. |
| Size and concentration 100µg and |
| Form lyophilized |
| Storage Instructions Lyophilized antibody is stable at 4°C for 2 years. Store the reconstituted solution in aliquots at -20°C for one year or at 4°C for 6 months after addition of 0.1% sodium azide by th |
| Storage buffer 10 mM PBS, pH 7.4, lyophilized |
| Purity immunogen affinty purifcation |
| Clonality monoclonal |
| Isotype IgG1 |
| Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
| Isotype control Mouse monocolonal IgG1 - Isotype Control |
| target relevance |
|---|
| Protein names Cadherin-3 (Placental cadherin) (P-cadherin) |
| Gene names CDH3,CDH3 CDHP |
| Mass 91418Da |
| Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Subellular location Cell membrane; Single-pass type I membrane protein. |
| Tissues Expressed in some normal epithelial tissues and in some carcinoma cell lines. |
| Structure Interacts with CDCP1 and CTNNB1. |
| Domain TOPO_DOM 1 |
| Involvement in disease DISEASE: Hypotrichosis congenital with juvenile macular dystrophy (HJMD) [MIM:601553]: A disorder characterized by congenital hypotrichosis, early hair loss, and severe degenerative changes of the retinal macula that culminate in blindness during the second to third decade of life. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS) [MIM:225280]: A form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. It is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly. Note=The disease is caused by variants affecting the gene represented in this entry. |
| Target Relevance information above includes information from UniProt accession: P22223 |
| The UniProt Consortium |
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
| relevant to this product |
|---|
| Western blot IHC |
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.