| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Epidiymis Protein 4 (HE4) |
| available sizes | 200 µg |
mouse anti-Epididymis Protein 4 (HE4) monoclonal antibody (2B13) 7192
$231.00
Antibody summary
- Mouse monoclonal to Epididymis Protein 4 (HE4)
- Suitable for: ELISA
- Isotype: IgG1
- 200 µg
mouse anti-Epididymis Protein 4 (HE4) monoclonal antibody (2B13) 7192
| antibody |
|---|
| Tested applications ELISA |
| Recommended dilutions ELISA: for sandwich ELISA use #34085 as capture antibody and #34084 or #34086 as detection antibody. End users should determine optimal antibody concentrations relative to their samples. |
| Immunogen Native human epididymis protein 4 (HE4) |
| Size and concentration 200µg and lot specific |
| Form liquid |
| Storage Instructions Store product at 4°C. |
| Storage buffer PBS, pH 7.2, 0.09% NaN3. |
| Purity protein affinity purification |
| Clonality monoclonal |
| Isotype IgG1 |
| Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
| Isotype control Mouse monocolonal IgG1 - Isotype Control |
| target relevance |
|---|
| Protein names WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4) (Major epididymis-specific protein E4) (Putative protease inhibitor WAP5) |
| Gene names WFDC2,WFDC2 HE4 WAP5 |
| Mass 12993Da |
| Function FUNCTION: Broad range protease inhibitor. {ECO:0000269|PubMed:23139753}. |
| Subellular location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15781627, ECO:0000269|PubMed:23139753}. |
| Tissues TISSUE SPECIFICITY: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. {ECO:0000269|PubMed:15781627}. |
| Structure SUBUNIT: Homotrimer; disulfide-linked. {ECO:0000269|PubMed:23139753}. |
| Involvement in disease DISEASE: Bronchiectasis and nasal polyposis (BENP) [MIM:620984]: An autosomal recessive destructive airway disease characterized by persistent abnormal dilatation of the bronchi, and severe chronic rhinosinusitis with nasal polyposis. Affected individuals suffer from sub-normal lung function, chronic productive cough, excessive sputum production, and recurrent sinopulmonary infections. {ECO:0000269|PubMed:38626355}. Note=The disease is caused by variants affecting the gene represented in this entry. |
| Target Relevance information above includes information from UniProt accession: Q14508 |
| The UniProt Consortium |
Data
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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