Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG1 |
clonality | monoclonal |
concentration | 1 mg/mL |
applications | ICC/IF, WB |
reactivity | Epidermal Growth Factor-like Protein 7 |
available sizes | 100 µg |
mouse anti-Epidermal Growth Factor-like Protein 7 monoclonal antibody (2H2) 7301
$520.00
Antibody summary
- Mouse monoclonal to Epidermal Growth Factor-like Protein 7
- Suitable for: WB,IHC,ELISA
- Isotype: IgG1
- 100 µg
mouse anti-Epidermal Growth Factor-like Protein 7 monoclonal antibody (2H2) 7301
antibody |
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Tested applications WB,IHC,IHC,ELISA |
Recommended dilutions ELISA: use at 1-10ug/ml Immunoblotting: User should use at 1-5ug/ml. A band of ~30kDa is detected. Immunohistochemistry: Use at 2- 10ug/ml. These are recommended concentrations. End user should determine optimal concentrations for their applications. |
Immunogen His-tagged EGFL-7 recombinant protein. Accession no. Q9UHF1. |
Size and concentration 100µg and |
Form lyophilized |
Storage Instructions This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles. |
Storage buffer Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose |
Purity protein affinty purification |
Clonality monoclonal |
Isotype IgG1 |
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
Isotype control Mouse monocolonal IgG1 - Isotype Control |
target relevance |
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Protein names Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1) |
Gene names EGFL7,EGFL7 MEGF7 UNQ187/PRO1449 |
Mass 29618Da |
Function FUNCTION: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis. {ECO:0000269|PubMed:23386126, ECO:0000269|PubMed:23639441}. |
Subellular location SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000269|PubMed:23386126}. |
Structure SUBUNIT: Interacts with ITGAV/ITGB3 in an RGD-dependent manner, increasing endothelial cell's motility. {ECO:0000269|PubMed:23386126}. |
Target Relevance information above includes information from UniProt accession : Q9UHF1 |
The UniProt Consortium |
Data
No results found |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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Western blot IHC |
Documents
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No results found |
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