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mouse anti-CYFRA21-1 monoclonal antibody (1X3) 4016

$324.00

Antibody summary

  • Mouse monoclonal to CYFRA21-1
  • Suitable for: ELISA
  • Isotype: IgG1
  • 200 µg
SKU: 4016parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG1

clonality

monoclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

CYFRA21-1

available sizes

200 µg

Available product – mouse anti-CYFRA21-1 monoclonal antibody (1X3) 4016

antibody
Tested applications
ELISA
Recommended dilutions
ELISA: for sandwich ELISA, use #34082 as capture antibody and #34083 as detection antibody.

End users should determine optimal antibody concentrations for their applications.
Immunogen
Soluble cytokeratin fraction purified from a human cell line
Size and concentration
200µg and lot specific
Form
liquid
Storage Instructions
Store product at 4°C.
Storage buffer
PBS, pH 7.4, 0.09% NaN3.
Purity
ion exchange
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monocolonal IgG1 - Isotype Control
target relevance
Protein names
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene names
KRT19,KRT19
Protein family
Intermediate filament family
Mass
44106Da
Function
FUNCTION: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. {ECO:0000269|PubMed:16000376}.
Tissues
TISSUE SPECIFICITY: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. {ECO:0000269|PubMed:16000376, ECO:0000269|PubMed:2468493, ECO:0000269|PubMed:2469734}.
Structure
SUBUNIT: Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein. {ECO:0000269|PubMed:10809736, ECO:0000269|PubMed:16000376}.; SUBUNIT: (Microbial infection) Interacts with hepatitis C virus/HCV core protein. {ECO:0000269|PubMed:15846844}.
Target Relevance information above includes information from UniProt accession : P08727
The UniProt Consortium

Data

No results found

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
ELISA

Documents

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