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mouse anti-Clostridium tetani Toxin monoclonal antibody (B416M) 2391

$527.00

Antibody summary

  • Mouse monoclonal to Clostridium tetani Toxin
  • Suitable for: WB,ELISA,Neutralizing/Inhibition
  • Isotype: IgG1
  • 500 µg
SKU: 2391parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG1

clonality

monoclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

Clostridium tetani Toxin

available sizes

500 µg

Available product – mouse anti-Clostridium tetani Toxin monoclonal antibody (B416M) 2391

antibody
Tested applications
WB,ELISA
Recommended dilutions
ELISAImmunoblotting A band of ~150,000 is detected.

End users should determine optimal dilutions for their applications.
Immunogen
Toxin purified from culture filtrate of C. tetani.
Size and concentration
500µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable at 4°C for short-term storage and for at least one (1) year at -20° to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Storage buffer
PBS, pH 7.4, 0.1% NaN3.
Purity
immunogen affinty purifcation
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monocolonal IgG1 - Isotype Control
target relevance
Protein names
Tetanus toxin (EC 3.4.24.68) (Tentoxylysin) [Cleaved into: Tetanus toxin light chain (Tetanus toxin chain L); Tetanus toxin heavy chain (Tetanus toxin chain H)]
Gene names
tetX,tetX CTC_p60
Protein family
Peptidase M27 family
Mass
150682Da
Function
FUNCTION: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Catalytic activity
CATALYTIC ACTIVITY: Reaction=Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.; EC=3.4.24.68;
Structure
SUBUNIT: The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.
Target Relevance information above includes information from UniProt accession : P04958
The UniProt Consortium

Data

No results found

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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