| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Cardiac Troponin T |
| available sizes | 100 µg |
mouse anti-Cardiac Tropinin T monoclonal antibody (7G7) 3805
$235.00
Antibody summary
- Mouse monoclonal to Cardiac Tropinin T
- Suitable for: ELISA
- Isotype: IgG1
- 100 µg
mouse anti-Cardiac Tropinin T monoclonal antibody (7G7) 3805
| antibody |
|---|
| Tested applications ELISA |
| Recommended dilutions These antibodies may be used in immunoassays to detect and quantitate human cardiac troponin T. They may also be used to affinity purify cardiac troponin T. |
| Immunogen Purified human cardiac troponin T. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Storage buffer PBS containing 0.1% NaN3 |
| Purity protein affinity purification |
| Clonality monoclonal |
| Isotype IgG1 |
| Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
| Isotype control Mouse monocolonal IgG1 - Isotype Control |
| target relevance |
|---|
| Homo sapiens TNNT2 Troponin T, cardiac muscle |
| Protein names Troponin T, cardiac muscle |
| Alternative names Cardiac muscle troponin T |
| Gene names TNNT2 |
| Protein family Belongs to the troponin T family |
| Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity |
| Post-translational modification Phosphorylation at Thr-213 by PRKCA induces significant reduction in myofilament calcium sensitivity and actomyosin ATPase activity |
| Involvement in disease Cardiomyopathy, familial hypertrophic, 2 A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. Cardiomyopathy, dilated, 1D A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Cardiomyopathy, familial restrictive 3 A heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function. |
| Keywords 3D-structure, Acetylation, Alternative splicing, Cardiomyopathy, Direct protein sequencing, Disease variant, Muscle protein, Phosphoprotein, Proteomics identification, Reference proteome |
| Sequence MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED EARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLR EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK |
| UniProt accession: P45379 |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What applications is the mouse anti-Cardiac Troponin T monoclonal antibody (7G7) suitable for?
This antibody is suitable for ELISA, immunocytochemistry/immunofluorescence (ICC/IF), and Western blot (WB) applications.
What is the recommended storage condition for this antibody to maintain its stability?
The antibody is stable for at least one year when stored at -20°C to -70°C. It is advised to store the product in appropriate aliquots to avoid multiple freeze-thaw cycles.
What is the host species and isotype of this monoclonal antibody?
The antibody is a mouse monoclonal antibody of the IgG1 isotype.
What is the immunogen used to generate the mouse anti-Cardiac Troponin T monoclonal antibody (7G7)?
The immunogen used is purified human cardiac troponin T.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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