| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | α-fetoprotein |
| available sizes | 200 µg |
mouse anti-α-Fetoprotein monoclonal antibody (AFP4A3) 6660
$231.00
Antibody summary
- Mouse monoclonal to α-Fetoprotein
- Suitable for: ELISA
- Isotype: IgG1
- 200 µg
mouse anti-α-Fetoprotein monoclonal antibody (AFP4A3) 6660
| target relevance |
|---|
| Protein names Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin) |
| Gene names AFP,AFP HPAFP |
| Protein family ALB/AFP/VDB family |
| Mass 68678Da |
| Function FUNCTION: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Subellular location SUBCELLULAR LOCATION: Secreted. |
| Tissues TISSUE SPECIFICITY: Plasma. Synthesized by the fetal liver and yolk sac. |
| Structure SUBUNIT: Dimeric and trimeric forms have been found in addition to the monomeric form. |
| Post-translational modification PTM: Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.; PTM: Sulfated. {ECO:0000269|PubMed:2414772}. |
| Involvement in disease DISEASE: Alpha-fetoprotein deficiency (AFPD) [MIM:615969]: A benign condition characterized by undetectable AFP levels in the amniotic fluid. Affected individuals are asymptomatic and present normal development. {ECO:0000269|PubMed:15280901, ECO:0000269|PubMed:18854864}. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Alpha-fetoprotein, hereditary persistence (HPAFP) [MIM:615970]: A benign autosomal dominant condition characterized by continued expression of alpha-fetoprotein in adult life. {ECO:0000269|PubMed:7684942}. Note=The disease is caused by variants affecting the gene represented in this entry. |
| Target Relevance information above includes information from UniProt accession: P02771 |
| The UniProt Consortium |
Data
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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