| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | α-fetoprotein |
| available sizes | 200 µg |
mouse anti-α-Fetoprotein monoclonal antibody (AFP4A3) 5101
$231.00
Antibody summary
- Mouse monoclonal to α-Fetoprotein
- Suitable for: ELISA
- Isotype: IgG1
- 200 µg
mouse anti-α-Fetoprotein monoclonal antibody (AFP4A3) 5101
| target relevance |
|---|
| Protein names Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin) |
| Gene names AFP,AFP HPAFP |
| Protein family ALB/AFP/VDB family |
| Mass 68678Da |
| Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Subellular location Secreted. |
| Tissues Plasma. Synthesized by the fetal liver and yolk sac. |
| Structure Dimeric and trimeric forms have been found in addition to the monomeric form. |
| Post-translational modification Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.; Sulfated. |
| Involvement in disease DISEASE: Alpha-fetoprotein deficiency (AFPD) [MIM:615969]: A benign condition characterized by undetectable AFP levels in the amniotic fluid. Affected individuals are asymptomatic and present normal development. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Alpha-fetoprotein, hereditary persistence (HPAFP) [MIM:615970]: A benign autosomal dominant condition characterized by continued expression of alpha-fetoprotein in adult life. Note=The disease is caused by variants affecting the gene represented in this entry. |
| Target Relevance information above includes information from UniProt accession: P02771 |
| The UniProt Consortium |
Data
| No results found |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
|---|
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
| # | |||
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| Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information. | |||
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