Leptospira IgG Control Serum BC125G

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Leptospira IgG Control Serum
Applications: ELISA
IgG control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC125G Categories: control serum, Virion/Serion kits Tags: ELISA control serum, IgG, Leptospira

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Leptospira reactive IgG
species reactivity	Leptospira
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Leptospira IgG Control Serum BC125G

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Leptospira biflexa Antigen (BA125VS) Leptospira IgG Control Serum (BC125G) Leptospira IgM Control Serum (BC125M) Leptospira IgG ELISA Kit (ESR125G) Leptospira IgM ELISA Kit (ESR125M)

target relevance

human antibody anti-Leptospira

Leptospira

Description
Spirochete bacterium that causes leptospirosis

Structure
Leptospira is a genus of thin, highly motile, Gram-negative spirochete bacteria belonging to the family Leptospiraceae. Members of the genus possess a characteristic tightly coiled helical morphology with hooked ends, often described as question mark-shaped. The bacteria are widely distributed in nature and are maintained in the kidneys of a broad range of wild and domestic animals, including rodents, cattle, pigs, dogs, and wildlife species. Pathogenic Leptospira species are shed into the environment through urine and can survive for extended periods in moist soil and freshwater. Human infection occurs through direct contact with infected animals or exposure to water, soil, or food contaminated with infected urine. Leptospira organisms are capable of penetrating mucous membranes and damaged skin, disseminating through the bloodstream, and infecting multiple organ systems.

Diagnosis
The diagnosis of leptospirosis is performed through serological, molecular, microbiological, and microscopic methods. The microscopic agglutination test (MAT) is considered the reference serological method and is widely used to detect antibodies against Leptospira. ELISA-based assays are commonly employed for screening and diagnosis due to their simplicity and sensitivity. Molecular methods such as polymerase chain reaction (PCR) provide rapid detection of Leptospira DNA during the early phase of infection before antibodies become detectable. Culture of Leptospira from blood, cerebrospinal fluid, or urine is possible but technically demanding and may require prolonged incubation. Laboratory findings often include elevated liver enzymes, renal dysfunction, thrombocytopenia, and inflammatory markers. Early diagnosis is essential because prompt antimicrobial therapy can reduce disease severity and complications.

Symptoms
Leptospirosis typically develops following an incubation period of approximately two to thirty days, most commonly seven to twelve days after exposure. The disease often begins abruptly with fever, chills, severe headache, muscle aches, particularly involving the calves and lower back, fatigue, nausea, vomiting, and conjunctival suffusion. Many infections are mild and self-limiting; however, severe disease may develop and is known as Weil's disease. This severe form is characterized by jaundice, acute kidney injury, liver dysfunction, hemorrhage, meningitis, myocarditis, respiratory distress, and multi-organ failure. Pulmonary involvement can result in life-threatening pulmonary hemorrhage syndrome. Without prompt treatment, severe leptospirosis can be fatal, particularly in elderly individuals and patients with significant organ involvement.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Leptospira IgG Control Serum BC125G?

The Leptospira IgG Control Serum BC125G is designed for use as an IgG control serum in ELISA assays, specifically pre-diluted for SERION ELISA classic and SERION ELISA antigen assays.

How should the Leptospira IgG Control Serum BC125G be stored to maintain its stability?

The control serum should be stored at a temperature range of 2-8°C to ensure proper stability and functionality.

Which species does the Leptospira IgG Control Serum BC125G target for reactivity?

This control serum targets IgG antibodies reactive to Leptospira species.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC125G protocol

Documents

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CO0169	Safety Data Sheet	QC certificate
CP0095	Safety Data Sheet	QC certificate
CQ0110	Safety Data Sheet	QC certificate

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Leptospira IgG Control Serum BC125G

Data

FAQ & Publications

Protocols

Documents

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Reviews

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