Echovirus IgM Control Serum BC135M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Echovirus IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC135M Categories: control serum, Virion/Serion kits Tags: Echovirus, ELISA control serum, IgM

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Echovirus reactive IgM
species reactivity	Echovirus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Echovirus IgM Control Serum BC135M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Echovirus Antigen (BA135VS01) Echovirus IgA Control Serum (BC135A) Echovirus IgG Control Serum (BC135G) Echovirus IgM Control Serum (BC135M) Echovirus IgG ELISA Kit (ESR135G) Echovirus IgA ELISA Kit (ESR135A) Echovirus IgM ELISA Kit (ESR135M)

target relevance

human antibody anti-Echovirus

Echovirus

Description
Group of enteroviruses that cause aseptic meningitis, febrile illness, and other systemic infections

Structure
Echoviruses (Enteric Cytopathic Human Orphan viruses) are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The viruses possess an icosahedral capsid that protects the viral genome and contributes to their resistance to environmental conditions and many disinfectants. Echoviruses are transmitted primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, viral replication occurs in the gastrointestinal tract and upper respiratory tract before dissemination through the bloodstream to various tissues and organs. More than thirty echovirus serotypes have been identified, and they are distributed worldwide. Echoviruses are among the most common causes of enteroviral infections and are frequently associated with outbreaks in children, although infections occur in all age groups.

Diagnosis
The diagnosis of echovirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic method due to its high sensitivity and specificity and can detect viral RNA in cerebrospinal fluid, stool samples, throat swabs, blood, and other clinical specimens. Viral culture may be performed in specialized laboratories but has largely been supplanted by molecular testing. Serological assays can detect echovirus-specific antibodies and may be useful for epidemiological investigations or retrospective diagnosis. Laboratory confirmation is particularly important in patients presenting with meningitis, encephalitis, neonatal infections, myocarditis, or unexplained febrile illness.

Symptoms
Echovirus infections produce a broad spectrum of clinical manifestations ranging from asymptomatic infection to severe systemic disease. Common symptoms include fever, headache, sore throat, fatigue, muscle aches, nausea, vomiting, abdominal pain, and rash. Echoviruses are a major cause of aseptic meningitis, which typically presents with fever, severe headache, neck stiffness, photophobia, and cerebrospinal fluid pleocytosis. Less commonly, echoviruses may cause encephalitis, myocarditis, pericarditis, hepatitis, conjunctivitis, and neonatal sepsis-like illness. Newborns and immunocompromised individuals are at increased risk of severe disease, which may result in multi-organ involvement and significant morbidity. Most infections are self-limiting and resolve without long-term complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Echovirus IgM Control Serum BC135M?

The Echovirus IgM Control Serum BC135M is primarily used as a control serum in ELISA assays to detect Echovirus reactive IgM antibodies.

Is the Echovirus IgM Control Serum BC135M ready to use directly in assays?

Yes, the serum is provided ready-to-use and pre-diluted specifically for SERION ELISA classic and SERION ELISA antigen assays.

How should the Echovirus IgM Control Serum BC135M be stored to maintain its stability?

The serum should be stored refrigerated at 2-8°C to preserve its integrity and functionality.

Does the Echovirus IgM Control Serum BC135M target IgM antibodies specific to Echovirus?

Yes, this control serum specifically targets Echovirus reactive IgM antibodies, making it suitable for indirect and quantitative ELISA assays involving Echovirus detection.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC135M protocol

Documents

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Echovirus IgM Control Serum BC135M

Data

FAQ & Publications

Protocols

Documents

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Reviews

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