Echovirus Antigen BA135VS01

$1,054.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Echovirus Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA135VS01 Category: Infectious disease proteins Tags: antigen, Echovirus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Echovirus
species reactivity	Echovirus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Echovirus Antigen BA135VS01

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Echovirus Antigen (BA135VS01) Echovirus IgA Control Serum (BC135A) Echovirus IgG Control Serum (BC135G) Echovirus IgM Control Serum (BC135M) Echovirus IgG ELISA Kit (ESR135G) Echovirus IgA ELISA Kit (ESR135A) Echovirus IgM ELISA Kit (ESR135M)

target relevance
Echovirus
Description Group of enteroviruses that cause aseptic meningitis, febrile illness, and other systemic infections
Structure Echoviruses (Enteric Cytopathic Human Orphan viruses) are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The viruses possess an icosahedral capsid that protects the viral genome and contributes to their resistance to environmental conditions and many disinfectants. Echoviruses are transmitted primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, viral replication occurs in the gastrointestinal tract and upper respiratory tract before dissemination through the bloodstream to various tissues and organs. More than thirty echovirus serotypes have been identified, and they are distributed worldwide. Echoviruses are among the most common causes of enteroviral infections and are frequently associated with outbreaks in children, although infections occur in all age groups.
Diagnosis The diagnosis of echovirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic method due to its high sensitivity and specificity and can detect viral RNA in cerebrospinal fluid, stool samples, throat swabs, blood, and other clinical specimens. Viral culture may be performed in specialized laboratories but has largely been supplanted by molecular testing. Serological assays can detect echovirus-specific antibodies and may be useful for epidemiological investigations or retrospective diagnosis. Laboratory confirmation is particularly important in patients presenting with meningitis, encephalitis, neonatal infections, myocarditis, or unexplained febrile illness.
Symptoms Echovirus infections produce a broad spectrum of clinical manifestations ranging from asymptomatic infection to severe systemic disease. Common symptoms include fever, headache, sore throat, fatigue, muscle aches, nausea, vomiting, abdominal pain, and rash. Echoviruses are a major cause of aseptic meningitis, which typically presents with fever, severe headache, neck stiffness, photophobia, and cerebrospinal fluid pleocytosis. Less commonly, echoviruses may cause encephalitis, myocarditis, pericarditis, hepatitis, conjunctivitis, and neonatal sepsis-like illness. Newborns and immunocompromised individuals are at increased risk of severe disease, which may result in multi-organ involvement and significant morbidity. Most infections are self-limiting and resolve without long-term complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Echovirus Antigen BA135VS01?

The Echovirus Antigen BA135VS01 is suitable for detection of IgA, IgG, and IgM antibodies in ELISA assays, specifically indirect and quantitative ELISA.

How should the Echovirus Antigen BA135VS01 be stored to maintain its stability?

This antigen should be stored at -65°C or lower and repeated freeze-thaw cycles should be avoided to preserve its integrity. Under these recommended storage conditions, it has a shelf life of 10 years from the date of manufacture.

Which species does the Echovirus Antigen BA135VS01 react with?

The product is reactive specifically with Echovirus species, which are associated with enteric diseases in humans and belong to the family Picornaviridae.

What is the form and concentration information provided for the Echovirus Antigen BA135VS01?

The antigen is supplied in liquid form with a lot-specific concentration that is specified in mg/mL. The available size of the product is 1 mg.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.