Immunohistochemistry (IHC) : Formalin-fixed, paraffin-embedded human pancreatic acinar cell carcinoma stained with anti-CPA1 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

rabbit anti-CPA1 monoclonal antibody (ZR450) 6129

$160.00 – $528.00

Antibody summary

Rabbit monoclonal to CPA1
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG
Control: Pancreatic acinar cell carcinoma
Visualization: Secreted and cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6129parent Category: antibody Tags: anatomy, CPA1, GI Pathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-CPA1 monoclonal antibody ZR450 6129
antibody
Database link:
human P15085
Tested applications
IHC
Recommended dilutions
Concentrated 1:100-200
Application Notes
Positive control: Pancreatic acinar cell carcinoma
Immunogen
Recombinant full-length human CPA1 protein
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Carboxypeptidase A1 (EC 3.4.17.1)
Protein family
Peptidase M14 family
Mass
47140Da
Function
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:20385563, PubMed:8806703). Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).
Catalytic activity
CATALYTIC ACTIVITY: Reaction=Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.; EC=3.4.17.1; Evidence=; CATALYTIC ACTIVITY: Reaction=H2O + leukotriene C4 = glycine + leukotriene F4; Xref=Rhea:RHEA:50740, ChEBI:CHEBI:15377, ChEBI:CHEBI:57305, ChEBI:CHEBI:57973, ChEBI:CHEBI:133618; Evidence=; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:50741; Evidence=;
Subellular location
Secreted .
Structure
Monomer. May form a complex with proelastase 2.
Domain
DOMAIN 121..414; /note="Peptidase M14"; /evidence="ECO:0000255|PROSITE-ProRule:PRU01379"
Target Relevance information above includes information from UniProt accession: P15085
The UniProt Consortium

Formalin-fixed, paraffin-embedded human pancreatic acinar cell carcinoma stained with anti-CPA1 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.