Immunohistochemistry (IHC) : Formalin-fixed, paraffin-embedded human pituitary adenoma stained with anti-TSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

mouse anti-Thyroid Stimulating Hormone monoclonal antibody (ZM294) 6384

$160.00 – $528.00

Antibody summary

Mouse monoclonal to Thyroid Stimulating Hormone
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1/κ
Control: Pituitary
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6384parent Category: antibody Tags: anatomy, Neuropathology/Endocrine, Thyroid Stimulating Hormone

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1/κ
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Thyroid Stimulating Hormone monoclonal antibody ZM294 6384

antibody
Database link: human P01222
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Applicaiton Notes Positive control: Pituitary
Immunogen Recombinant human TSH beta fragment
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names Thyrotropin subunit beta (Thyroid-stimulating hormone subunit beta) (TSH-B) (TSH-beta) (Thyrotropin beta chain) (Thyrotropin alfa)
Protein family Glycoprotein hormones subunit beta family
Mass 15639Da
Function Indispensable for the control of thyroid structure and metabolism.
Subellular location Secreted.
Structure Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
Involvement in disease Hypothyroidism, congenital, non-goitrous, 4 (CHNG4) [MIM:275100]: A form of central hypothyroidism, a disorder characterized by insufficient stimulation by thyroid stimulating hormone of an otherwise normal thyroid gland. CHNG4 is an autosomal recessive form characterized by isolated thyrotropin deficiency that, if untreated, results in severe growth retardation and intellectual disability. Note=The disease is caused by variants affecting the gene represented in this entry.
Target Relevance information above includes information from UniProt accession: P01222
The UniProt Consortium

Data

Formalin-fixed, paraffin-embedded human pituitary adenoma stained with anti-TSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.