Immunohistochemistry (IHC) : Formalin-fixed, paraffin-embedded human pituitary adenoma stained with anti-TSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

mouse anti-Thyroid Stimulating Hormone monoclonal antibody (ZM294) 6384

$160.00 – $528.00

Antibody summary

Mouse monoclonal to Thyroid Stimulating Hormone
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1/κ
Control: Pituitary
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6384parent Category: antibody Tags: anatomy, Neuropathology/Endocrine, Thyroid Stimulating Hormone

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1/κ
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Thyroid Stimulating Hormone monoclonal antibody ZM294 6384
antibody
Database link:
human P01222
Tested applications
IHC
Recommended dilutions
Concentrated 1:100-200
Application Notes
Positive control: Pituitary
Immunogen
Recombinant human TSH beta fragment
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monoclonal IgG1 - Isotype Control
target relevance
Protein names
Thyrotropin subunit beta (Thyroid-stimulating hormone subunit beta) (TSH-B) (TSH-beta) (Thyrotropin beta chain) (Thyrotropin alfa)
Protein family
Glycoprotein hormones subunit beta family
Mass
15639Da
Function
Indispensable for the control of thyroid structure and metabolism.
Subellular location
Secreted.
Structure
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
Involvement in disease
Hypothyroidism, congenital, non-goitrous, 4 (CHNG4) [MIM:275100]: A form of central hypothyroidism, a disorder characterized by insufficient stimulation by thyroid stimulating hormone of an otherwise normal thyroid gland. CHNG4 is an autosomal recessive form characterized by isolated thyrotropin deficiency that, if untreated, results in severe growth retardation and intellectual disability. Note=The disease is caused by variants affecting the gene represented in this entry.
Target Relevance information above includes information from UniProt accession: P01222
The UniProt Consortium

Formalin-fixed, paraffin-embedded human pituitary adenoma stained with anti-TSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.