Immunohistochemistry (IHC) : Human parathyroid gland stained with anti-PTH antibody using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining in glandular cells.

mouse anti-Parathyroid hormone (PTH) monoclonal antibody (ZM207) 6431

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to Parathyroid hormone (PTH)
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG2b
Control: Parathyroid
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6431parent Category: antibody Tags: anatomy, Neuropathology/Endocrine, Parathyroid hormone (PTH)

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG2b
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Parathyroid hormone (PTH) monoclonal antibody ZM207 6431

antibody
Database link: human P01270
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Parathyroid
Immunogen Recombinant fragment corresponding to the C-terminus of human TP63 protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG2b
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG2b - Isotype Control

target relevance
Protein names Parathyroid hormone (PTH) (Parathormone) (Parathyrin)
Gene names PTH,PTH
Protein family Parathyroid hormone family
Mass 12861Da
Function FUNCTION: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. {ECO:0000269\|PubMed:21076856}.
Subellular location SUBCELLULAR LOCATION: Secreted.
Structure SUBUNIT: Interacts with PTH1R (via N-terminal extracellular domain). {ECO:0000269\|PubMed:18375760}.
Involvement in disease DISEASE: Hypoparathyroidism, familial isolated, 1 (FIH1) [MIM:146200]: A form of hypoparathyroidism, a disorder characterized by hypocalcemia and hyperphosphatemia due to a deficiency of parathyroid hormone. Clinical features include seizures, tetany and cramps. FIH1 inheritance can be autosomal dominant or recessive. {ECO:0000269\|PubMed:10523031, ECO:0000269\|PubMed:18056632, ECO:0000269\|PubMed:2212001}. Note=The disease is caused by variants affecting the gene represented in this entry.
Target Relevance information above includes information from UniProt accession: P01270
The UniProt Consortium

Data

Human parathyroid gland stained with anti-PTH antibody using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining in glandular cells.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.