Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG2b |
clonality | monoclonal |
concentration | concentrate, predilute |
applications | IHC |
reactivity | human |
available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
mouse anti-Parathyroid hormone (PTH) monoclonal antibody (ZM207) 6431
$160.00 – $528.00
Antibody summary
- Mouse monoclonal to Parathyroid hormone (PTH)
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG2b
- Control: Parathyroid
- Visualization: Cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
mouse anti-Parathyroid hormone (PTH) monoclonal antibody ZM207 6431
target relevance |
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Protein names Parathyroid hormone (PTH) (Parathormone) (Parathyrin) |
Gene names PTH,PTH |
Protein family Parathyroid hormone family |
Mass 9606Da |
Function PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
Subellular location Secreted. |
Structure Interacts with PTH1R (via N-terminal extracellular domain). |
Involvement in disease DISEASE: Hypoparathyroidism, familial isolated, 1 (FIH1) [MIM:146200]: A form of hypoparathyroidism, a disorder characterized by hypocalcemia and hyperphosphatemia due to a deficiency of parathyroid hormone. Clinical features include seizures, tetany and cramps. FIH1 inheritance can be autosomal dominant or recessive. Note=The disease is caused by variants affecting the gene represented in this entry. |
Target Relevance information above includes information from UniProt accession: P01270 |
The UniProt Consortium |
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Human parathyroid gland stained with anti-PTH antibody using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining in glandular cells. |
Publications
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We haven't added any publications to our database yet. |
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IHC |
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