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Measles Virus IgM ELISA kit-SERION classic ESR102M

$364.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Measles Virus IgM ELISA Kit
  • Suitable for IgM detection
  • Ready-to-use
  • 96 tests
SKU: ESR102M Category: Tags: ,
Weight 1 lbs
Dimensions 9 × 5 × 2 in
target

Human Measles Virus reactive IgM

species reactivity

Measles Virus

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Measles Virus IgM ELISA Kit ESR102M

kit
Target name
Human Measles Virus IgM
Assay type
Indirect ELISA
Overview
The SERION ELISA classic Masern/Measles Virus IgG and IgM tests are quantitative and qualitative immunoassays for the detection of human antibodies in serum or plasma directed against Measles Virus. The SERION ELISA classic Masern/Measles Virus IgM test is recommended for the determination of acute infections. The SERION ELISA classic Masern/Measles Virus IgG assay is recommended for determination of immune status and for detection of intrathecal synthesized IgG antibodies in cerebrospinal fluid for CSF diagnostics.
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.
Components
Break apart microtiter test strips each with antigen coated single wells 8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgM-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
2-8°C
Associated products
Measles Antigen (BA102VS)
Measles Virus IgG Control Serum (BC102G)
Measles Virus IgG ELISA Kit (ESR102G)
Measles Virus IgM Control Serum (BC102M)
Measles Antigen [premium] (BA102VS-S)
Additional information
Additional Serion Kit Information
target relevance
Organism
Measles morbillivirus (MeV)
Protein names
Measles Virus
Structure and strains
The measles virus genome is typically 15,894-nucleotides long and encodes eight proteins. The WHO currently recognizes 8 clades of measles (A-H). Subtypes are designed with numerals-A1, D2 etc. Currently, 23 subtypes are recognized. The 450 nucleotides that code for the C-terminal 150 amino acids of N are the minimum amount of sequence data required for genotyping a measles virus isolate.

Despite the variety of measles genotypes, there is only one measles serotype. Antibodies to measles bind to the hemagglutinin protein. Thus, antibodies against one genotype (such as the vaccine strain) protect against all other genotypes.

Detection and diagnosis
Demonstration of IgM antibodies is commonly used as evidence for an acute infection and provides positive test results early on with the onset of symptoms. The demonstration of IgG antibodies serves primarily for immune status and vaccination control as well as for confirmation of Measles Virus infections. The detection of IgG antibodies in CSF samples is particularly recommended in cases of suspected encephalitis and multiple sclerosis.

Data

FAQ & Publications

Frequently Asked Questions
What type of samples can be used with the Measles Virus IgM ELISA Kit ESR102M?
The kit is compatible with serum, plasma, and whole blood samples for the detection of Measles Virus IgM antibodies.
Why is RF-Absorbent Z200 recommended for use with this IgM ELISA kit?
RF-Absorbent Z200 is recommended to remove IgM rheumatoid factors from serum and plasma samples prior to testing, which helps to eliminate false negative results and improve signal specificity.
How should the Measles Virus IgM ELISA Kit ESR102M be stored to maintain stability?
The kit components should be stored refrigerated at 2-8°C to preserve their activity and ensure reliable assay performance.
What is the assay format and detection type employed by this Measles Virus IgM ELISA kit?
This is an indirect and quantitative ELISA designed to detect human antibodies specific to Measles Virus IgM.
Is the Measles Virus IgM ELISA Kit ESR102M suitable for detecting acute measles infections?
Yes, the kit is specifically recommended for the determination of acute measles virus infections by detecting IgM antibodies.
Publications
pmid title authors citation
38627149 Measles outbreak associated with a preschool setting among partially vaccinated children in the Tel Aviv District, Israel, October 2023. Rivka Sheffer, Efrat Bucris, Ziva Amitai, Victoria Indenbaum, Yaniv Lustig, Michal Savion, Naama Nuss, Shepherd Roee Singer, Sharon Alroy Preis, Sharon Almagor, Eyal Leshem, Matanelle Salama Vaccine 42:3153-3156
38275299 Diagnostic accuracy of commercially available serological tests for the detection of measles and rubella viruses: a systematic review and meta-analysis. Vanessa Zubach, Jennifer Beirnes, Shannon Hayes, Alberto Severini, Joanne Hiebert J Clin Microbiol 62:e0133923
36409098 Performance Characteristics of Six Immunoglobulin M Enzyme-Linked Immunosorbent Assays Used for Laboratory Confirmation of Measles. Sun B Sowers, Kiana Anthony, Sara Mercader, Heather Colley, Stephen N Crooke, Paul A Rota, Donald R Latner, Carole J Hickman J Clin Microbiol 60:e0122722
34705533 Evaluation of Diagnostic Accuracy of Eight Commercial Assays for the Detection of Rubella Virus-Specific IgM Antibodies. Joanne Hiebert, Vanessa Zubach, Carmen L Charlton, Jayne Fenton, Graham A Tipples, Kevin Fonseca, Alberto Severini J Clin Microbiol 60:e0159721
31377078 Study on factors associated with seroprotection after measles vaccination in children of 6-14 years in Eastern China. Rui Yan, Hanqing He, Yang Zhou, Shuyun Xie, Xuan Deng, Xuewen Tang Vaccine 37:5185-5190

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR102M protocol

Documents

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EP0036 Safety Data Sheet QC certificate
EQ0064 Safety Data Sheet QC certificate

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