t Human Campylobacter IgA Lateral flow dipstick kit 6273 – benchmark antibodies
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Human Campylobacter IgA Lateral flow dipstick kit 6273

Human Campylobacter IgA Lateral flow dipstick kit 6273

$487.00

Summary

  • Mikrogen diagnostik lateral flow device (dipstick) for research use (RUO)
  • Human Campylobacter IgA Lateral flow dipstick kit 6273
  • Suitable for IgA detection
  • Ready-to-use
  • 20 tests
SKU: 6273 Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Human Campylobacter IgA

species reactivity

Human Campylobacter

applications

Lateral flow (dipstick)

assay type

Indirect & qualitative

available sizes

20 test kits

Human Campylobacter IgA Lateral flow dipstick kit 6273

kit
Assay type
Sandwich assay, lateral flow (dipstick)
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Components
10X Wash Buffer100 mL
TMB Substrate40 mL
Milk Powder5 g
Instructions for Use1 Each
Evaluation Form1 Each
Test Strips2 kits of [2 Vials x 10 Each]
Anti-Human IgA Conjugate500 μL
Positive Control140 μL
Negative Control140 μL
Storage
Store at 2-8°C.
Additional information

Mikrogen recomLine Campylobacter tests are serological, qualitative in vitro tests for the detection of IgG and IgA antibodies against immunodominant antigens of Campylobacter jejuni and Campylobacter coli. After going through a Campylobacter infection or in case of a persistent infection which is primarily detected through stool culture, our recomLine Campylobacter tests with separately lined up recombinantly produced antigens allow the determination of specific antibodies for the clarification of post-infectious complications (e.g., Campylobacter-induced arthritis).

Advantages
  • Separate detection of IgG and IgA antibodies.
  • Simple and clear interpretation due to easy-to-read banding.
  • Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.
  • Highest sensitivity and specificity through use of recombinant, immunodominant antigens:
Bands
DescriptionAntigenMolecular Weight [kDa]
Major outer membrane protein (porA)MOMP46
Cell-binding factor 2 (cbf2)PEB431
Major antigenic peptide PEB2PEB227
Major cell-binding factor (cbf1)PEB128
Peptidoglycan-associated lipoproteinOMP1818
Putative ATP/GTP binding proteinP3939
target relevance
Organism
Campylobacter jejuni
Structure and strains
Campylobacter jejuni is a species of pathogenic bacteria, one of the most common causes of food poisoning in Europe and in the US. The vast majority of cases occur as isolated events, not as part of recognized outbreaks.Active surveillance through the Foodborne Diseases Active Surveillance Network (FoodNet) indicates that about 20 cases are diagnosed each year for each 100,000 people in the US, while many more cases are undiagnosed or unreported; the CDC estimates a total of 1.5 million infections every year. The European Food Safety Authority reported 246,571 cases in 2018, and estimated approximately nine million cases of human campylobacteriosis per year in the European Union.
Disease
Campylobacter is a bacteria consisting of more than 20 species occuring worldwide. In particular, Campylobacter jejuni is associated with human diseases in industrialized countries. The main reservoirs of the are warmblooded domestic and wild animals.

Human Campylobacteriosis is primarily a foodborne disease. Insufficiently heated, contaminated poultry and poultry products (eggs excluded) are the main sources of infection. A clinical manifestation of Campylobacter jejuni infections is acute enteritis which is accompanied by fever (38 - 40°C), headache, myalgia, anthralgia and weariness. Normally infections are self limiting, but 5 to 10% of untreated patients develop relapses. Rare complications of infection are Guillain-Barre-Syndrome, an inflammatory disease of the peripheral nervous system, and reactive arthritis. Diagnosis Campylobacter jejuni infections are usually detected by pathogen isolations from stool and blood samples. I
Detection and diagnosis
Campylobacter jejuni infections are usually detected by pathogen isolations from stool and blood samples. In recent years, serological diagnosis of Campylobacter jejuni infections has developed into an important routine diagnostic procedure. To analyze the etiology of severe complications, such as reactive arthritis and GBS, reliable serological ELISA tests are required, since these diseases usually develop up to three weeks after Campylobacter jejuni infection. In such cases, stool culture testing is not suitable since isolation attempts are usually unsuccessful at this stage.

Publications

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Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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