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Ki67 antibodies


Ki67, also known as the Ki-67 antigen, is a widely recognized and extensively used marker in scientific research, particularly in the fields of cell biology, cancer research, and clinical pathology. Ki67 is a nuclear protein that is expressed during all active phases of the cell cycle (G1, S, G2, and mitosis) but is absent in quiescent or resting cells (G0). As a result, it serves as a valuable tool to identify and quantify actively proliferating cells in tissues and cell cultures. Immunohistochemistry and immunofluorescence techniques utilizing Ki67 antibodies allow researchers to visualize and measure the proportion of proliferating cells in various tissues and tumors, providing valuable information about cellular proliferation rates, growth patterns, and disease prognosis. In cancer research, Ki67 expression has been correlated with tumor aggressiveness and response to therapy, making it a useful prognostic marker for certain types of cancers. Moreover, Ki67 is an essential tool in basic research to study cell cycle dynamics, cell proliferation regulation, and the effects of various experimental treatments on cellular growth.