| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Human Measles Virus Antigen |
| species reactivity | Measles Virus |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available size | 1 mg |
Measles Virus (Premium) Antigen BA102VS-S
$835.00
Summary
- Virion/Serion Immunologics Antigen for research use (RUO)
- Measles Virus (Premium) Antigen, recombinant
- Suitable for detection of IgA, IgG & IgM antibodies in ELISA
- Lot specific concentration, specified in mg/mL
- 1 mg
Measles Virus (Premium) Antigen BA102VS-S
| kit |
|---|
| Overview The native Measles Virus Antigen Premium (BA102VS-S) is produced by cultivation of measles virus (strain Edmonston) in Vero cells and a subsequent concentration of the culture supernatant by ultra-filtration and ultra-centrifugation. The resulting antigen preparation consists of a high concentration of virus and viral components that enable very sensitive and specific detection of IgG and IgM antibodies. |
| Research area Infectious Disease |
| Storage Store at -65µC. Avoid freeze/thaw cycles. Sonicate before use. |
| Form liquid |
| Associated products Measles Antigen (BA102VS) Measles Virus IgG Control Serum (BC102G) Measles Virus IgG ELISA Kit (ESR102G) Measles Virus IgM ELISA Kit (ESR102M) Measles Virus IgM Control Serum (BC102M) |
| Additional information Additional Serion Kit Information |
| target relevance |
|---|
| Organism Measles morbillivirus (MeV) |
| Structure and strains The measles virus genome is typically 15,894???nucleotides long and encodes eight proteins. The WHO currently recognises 8 clades of measles (A???H). Subtypes are designed with numerals???A1, D2 etc. Currently, 23 subtypes are recognised. The 450 nucleotides that code for the C???terminal 150 amino acids of N are the minimum amount of sequence data required for genotyping a measles virus isolate. Despite the variety of measles genotypes, there is only one measles serotype. Antibodies to measles bind to the hemagglutinin protein. Thus, antibodies against one genotype (such as the vaccine strain) protect against all other genotypes. |
| Disease Measles Viruses occur worldwide and belong to the family of paramyxoviridae. The pathogen is transmitted by close contact with infected individuals primarily by droplet infection. Due to the high infectivity of the virus, measles is usually aquired during childhood. After an incubation period of 10 to 12 days Koplik??s spots typically appear on oral mucosa in 60 to 70% of cases. In the course of the prodromal period flu-like symptoms may escalate until the typical measles exanthema arises with sharply increasing fever. The exanthema spreads from face to the extremities. The clinical symptoms peak within several days with a corresponding rapid recovery. Complications occur frequently, mainly pneumonia and encephalitis. Infection results in a life-long immunity. A combination of attenuated life vaccines for mumps, measles and rubella (MMR) has been available for several years. |
| Detection and diagnosis Demonstration of IgM antibodies is commonly used as evidence for an acute infection and provides positive test results early on with the onset of symptoms. The demonstration of IgG antibodies serves primarily for immune status and vaccination control as well as for confirmation of Measles Virus infections. The detection of IgG antibodies in CSF samples is particularly recommended in cases of suspected encephalitis and multiple sclerosis. |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| BA102VS-S protocol |
Documents
| Product data sheet |
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| BA102VS-S |
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