Human Campylobacter IgA Lateral flow dipstick kit 6273

$487.00

Summary

Mikrogen diagnostik lateral flow device (dipstick) for research use (RUO)
Human Campylobacter IgA Lateral flow dipstick kit 6273
Suitable for IgA detection
Ready-to-use
20 tests

SKU: 6273 Category: Mikrogen kits Tags: Campylobacter, IgG, Lateral Flow Dipsticks

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Campylobacter IgA
species reactivity	Human Campylobacter
applications	Lateral flow (dipstick)
assay type	Indirect & qualitative
available sizes	20 test kits

Human Campylobacter IgA Lateral flow dipstick kit 6273

Assay type
Sandwich assay, lateral flow (dipstick)

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

10X Wash Buffer	100 mL
TMB Substrate	40 mL
Milk Powder	5 g
Instructions for Use	1 Each
Evaluation Form	1 Each
Test Strips	2 kits of [2 Vials x 10 Each]
Anti-Human IgA Conjugate	500 µL
Positive Control	140 µL
Negative Control	140 µL

Storage
Store at 2-8°C.

Additional information

Mikrogen recomLine Campylobacter tests are serological, qualitative in vitro tests for the detection of IgG and IgA antibodies against immunodominant antigens of Campylobacter jejuni and Campylobacter coli. After going through a Campylobacter infection or in case of a persistent infection which is primarily detected through stool culture, our recomLine Campylobacter tests with separately lined up recombinantly produced antigens allow the determination of specific antibodies for the clarification of post-infectious complications (e.g., Campylobacter-induced arthritis).

Advantages

Separate detection of IgG and IgA antibodies.
Simple and clear interpretation due to easy-to-read banding.
Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.
Highest sensitivity and specificity through use of recombinant, immunodominant antigens:

Bands

Description	Antigen	Molecular Weight [kDa]
Major outer membrane protein (porA)	MOMP	46
Cell-binding factor 2 (cbf2)	PEB4	31
Major antigenic peptide PEB2	PEB2	27
Major cell-binding factor (cbf1)	PEB1	28
Peptidoglycan-associated lipoprotein	OMP18	18
Putative ATP/GTP binding protein	P39	39

target relevance

human antibody anti-Campylobacter

Campylobacter

Description
Bacterial genus that causes campylobacteriosis and gastrointestinal infections

Structure
Campylobacter is a genus of Gram-negative, microaerophilic, spiral-shaped or curved rod bacteria belonging to the family Campylobacteraceae. Members of the genus are highly motile due to the presence of polar flagella, which enable corkscrew-like movement through mucus and host tissues. The most clinically significant species are Campylobacter jejuni and Campylobacter coli, which are among the leading causes of bacterial gastroenteritis worldwide. Campylobacter species commonly colonize the intestinal tracts of poultry, cattle, and other animals and are transmitted to humans primarily through contaminated food, water, or direct animal contact. The bacteria possess numerous virulence factors that facilitate adherence to and invasion of intestinal epithelial cells, resulting in inflammation and tissue damage.

Diagnosis
The diagnosis of Campylobacter infection is performed through microbiological, molecular, and antigen detection methods. Isolation of the organism from stool specimens using selective culture media under microaerophilic conditions remains a standard diagnostic approach. Molecular methods such as polymerase chain reaction (PCR) provide rapid and highly sensitive detection of Campylobacter DNA and are increasingly incorporated into multiplex gastrointestinal pathogen panels. Antigen detection assays may also be used in some clinical laboratories. Laboratory confirmation is important because the symptoms of campylobacteriosis overlap with those caused by numerous other bacterial, viral, and parasitic enteric pathogens.

Symptoms
Campylobacter infection, known as campylobacteriosis, typically develops following an incubation period of approximately two to five days after exposure. Common symptoms include diarrhea, which may be bloody, abdominal pain, fever, nausea, vomiting, headache, and malaise. The abdominal pain may be severe and can mimic acute appendicitis. Most infections are self-limiting and resolve within one week; however, severe disease may occur in young children, elderly individuals, and immunocompromised patients. Rare but important complications include bacteremia, reactive arthritis, irritable bowel syndrome, and Guillain-Barré syndrome, an autoimmune neurological disorder that can result in muscle weakness and paralysis.

Data

FAQ & Publications

Frequently Asked Questions

What type of antibodies does the Human Campylobacter IgA Lateral Flow Dipstick Kit detect?

The kit specifically detects human IgA antibodies directed against Campylobacter species.

Which sample types are compatible with the Human Campylobacter IgA Lateral Flow Dipstick Kit?

This lateral flow assay can be used with serum, plasma, and whole blood samples for detection of IgA antibodies.

How should the Human Campylobacter IgA Lateral Flow Dipstick Kit be stored to maintain stability?

The kit should be stored refrigerated at 2-8°C to ensure proper preservation of reagents and test strips.

What advantages does this kit offer in terms of assay specificity and sensitivity?

The kit utilizes recombinant immunodominant antigens of Campylobacter jejuni and coli, providing high sensitivity and specificity for IgA antibody detection through a sandwich lateral flow assay format.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
This product has moved to a digital protocol. Please use the URL provided on the product packaging to access the electronic Instructions for Use (eIFU). 6273 protocol