Human Chlamydia IgG Lateral flow dipstick kit 6172

$487.00

Summary

Mikrogen diagnostik lateral flow device (dipstick) for research use (RUO)
Human Chlamydia IgG Lateral flow dipstick kit 6172
Suitable for IgG detection
Ready-to-use
20 tests

SKU: 6172 Category: Mikrogen kits Tags: Chlamydia, IgG, Lateral Flow Dipsticks

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Chlamydia IgG
species reactivity	Chlamydia (C. pneumoniae, C. trachomatis, C. psittaci)
applications	Lateral flow (dipstick)
assay type	Indirect & qualitative
available sizes	20 test kits

Human Chlamydia IgG Lateral flow dipstick kit 6172

Assay type
Sandwich assay, lateral flow (dipstick)

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

10X Wash Buffer	100 mL
TMB Substrate	40 mL
Milk Powder	5 g
Instructions for Use	1 Each
Evaluation Form	1 Each
Test Strips	2 kits of [2 Vials x 10 Each]
Anti-Human IgG Conjugate	500 µL
Positive Control	140 µL
Negative Control	140 µL

Storage
Store at 2-8°C.

Additional information

Mikrogen recomLine Helicobacter 2.0 tests are serological, qualitative in vitro line immunoassays for the detection of antibodies against ten selected Helicobacter pylori antigens. The detection of antibodies against the two most important virulence factors CagA and VacA are of high diagnostic importance. These two virulence factors significantly increase the risk for premalignant changes, gastric carcinoma, MALT lymphoma, and ulcers. Humoral immune responses against the GroEL, HtrA, NapA, HP231, and CtkA biomarkers are associated with more severe disease progression.

Advantages

Sensitivity: > 99% IgG positive results of gold standard positive patients.
Specificity: 100% IgG and IgA negative results of gold standard negative patients.
Excellent correlation with the gold standard of Helicobacter pylori diagnostics - culture and histology.
Reliable results at all times, even with low colonization density.
Identification of highly virulent Helicobacter pylori type I infections using CagA.
Detection of antibodies against ten relevant biomarkers and virulence factors associated with more severe disease progression.
Simple and clear interpretation through easy-to-read banding.
Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.
Highest sensitivity and specificity through the use of recombinant antigens:

target relevance

human antibody anti-Toxoplasma gondii

Toxoplasma gondii

Description
Protozoan parasite that causes toxoplasmosis

Structure
Toxoplasma gondii is an obligate intracellular protozoan parasite belonging to the phylum Apicomplexa. The parasite has a complex life cycle involving both sexual and asexual stages. Members of the cat family (Felidae) serve as the definitive hosts in which sexual reproduction occurs, while a wide range of warm-blooded animals, including humans, act as intermediate hosts. T. gondii exists in several developmental forms, including rapidly dividing tachyzoites, slowly replicating tissue cysts containing bradyzoites, and environmentally resistant oocysts shed in feline feces. The parasite is distributed worldwide and is one of the most common parasitic infections of humans. Following infection, T. gondii can establish lifelong latent infection within muscle and neural tissues through the formation of tissue cysts.

Diagnosis
The diagnosis of Toxoplasma gondii infection is performed through serological, molecular, histological, and microbiological methods. Serological testing is the most commonly used diagnostic approach and includes detection of Toxoplasma-specific IgM and IgG antibodies using ELISA and other immunoassays. Measurement of antibody avidity may help distinguish recent from past infection. Molecular techniques such as polymerase chain reaction (PCR) are widely used for detecting parasite DNA in blood, cerebrospinal fluid, amniotic fluid, and tissue specimens, particularly in congenital infections and immunocompromised patients. Histopathological examination and direct visualization of parasites may also aid diagnosis in selected cases. Early diagnosis is especially important during pregnancy because of the risk of congenital transmission.

Symptoms
Most immunocompetent individuals infected with Toxoplasma gondii remain asymptomatic or develop mild flu-like symptoms, including fever, fatigue, headache, muscle aches, and lymphadenopathy. Following primary infection, the parasite establishes latent infection that may persist for life. In immunocompromised individuals, including patients with advanced HIV infection, organ transplant recipients, and individuals receiving immunosuppressive therapy, reactivation of latent infection can cause severe disease, particularly toxoplasmic encephalitis characterized by headache, confusion, seizures, focal neurological deficits, and altered mental status. Congenital toxoplasmosis can occur when infection is acquired during pregnancy and may result in miscarriage, stillbirth, hydrocephalus, intracranial calcifications, chorioretinitis, vision impairment, developmental delay, and other severe neurological complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Human Chlamydia IgG Lateral Flow Dipstick Kit 6172?

The Human Chlamydia IgG Lateral Flow Dipstick Kit 6172 is designed for qualitative detection of IgG antibodies against human pathogenic Chlamydia species using a lateral flow (dipstick) assay format, suitable for research use only.

Which Chlamydia species are detected by this lateral flow dipstick kit?

This kit detects IgG antibodies reactive to the three human pathogenic Chlamydia species: Chlamydia pneumoniae, Chlamydia trachomatis, and Chlamydia psittaci.

What types of samples can be used with the Human Chlamydia IgG Lateral Flow Dipstick Kit?

The assay can be performed using serum, plasma, or whole blood samples for detection of Chlamydia-specific IgG antibodies.

How should the Human Chlamydia IgG Lateral Flow Dipstick Kit 6172 be stored to maintain stability?

The kit and its components should be stored at 2-8°C to ensure optimal stability and performance.

Can this kit be used for both screening and confirmatory testing of Chlamydia infections?

Yes, the kit is suitable for use as both a screening and a confirmatory assay due to its use of recombinant, species-specific antigens providing high sensitivity and specificity.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
This product has moved to a digital protocol. Please use the URL provided on the product packaging to access the electronic Instructions for Use (eIFU). 6172 protocol