Zika Virus NS1 Control Antigen BA149R01

$882.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Zika Virus NS1 Control Antigen, recombinant
G333
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA149R01 Category: Infectious disease proteins Tags: antigen, Zika Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Zika Virus NS1
species reactivity	Zika Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Zika Virus NS1 Control Antigen BA149R01

kit
Research area Infectious Disease
Storage Store at -65°C. Avoid freeze/thaw cycles. Sonicate before use.
Form liquid
Associated products Zika Virus NS1 Control Antigen (BA149R01) Zika Virus Human IgA Assay Control (BC149A) Zika Virus Human IgG Assay Control (BC149G) Zika Virus Human IgM Assay Control (BC149M) Zika Virus IgA ELISA Kit (ESR149A) Zika Virus IgG ELISA Kit (ESR149G) Zika Virus IgM ELISA Kit (ESR149M)

target relevance
Zika Virus
Description Virus that causes Zika virus disease and congenital Zika syndrome
Structure Zika virus is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Flavivirus within the family Flaviviridae. The virus is closely related to dengue virus, yellow fever virus, West Nile virus, and Japanese encephalitis virus. Zika virus is transmitted primarily through the bites of infected Aedes mosquitoes, particularly Aedes aegypti and Aedes albopictus, although transmission can also occur through sexual contact, blood transfusion, organ transplantation, and from mother to fetus during pregnancy. Following infection, the virus replicates in skin cells, lymphoid tissues, and other organs before disseminating throughout the body. Zika virus gained international attention during the 2015–2016 outbreaks in the Americas due to its association with congenital abnormalities and neurological complications.
Diagnosis The diagnosis of Zika virus infection is performed through molecular and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic method during the acute phase of infection and allows direct detection of viral RNA in serum, plasma, urine, saliva, amniotic fluid, and other clinical specimens. Serological testing, including ELISA-based detection of Zika virus-specific IgM antibodies, may be used after the viremic phase has passed. However, interpretation of serological results can be challenging due to cross-reactivity with antibodies generated against other flaviviruses such as dengue virus. Plaque reduction neutralization tests (PRNT) may be used to confirm infection and distinguish Zika virus from related flaviviral infections.
Symptoms Zika virus infection is often asymptomatic, with approximately 70–80% of infected individuals showing no clinical signs of disease. When symptoms occur, they typically develop after an incubation period of three to fourteen days and include mild fever, maculopapular rash, conjunctivitis, headache, muscle aches, joint pain, and fatigue. Symptoms are generally mild and self-limiting, resolving within several days to one week. Despite the typically mild nature of acute infection, Zika virus can cause serious complications. Infection during pregnancy may result in congenital Zika syndrome, characterized by microcephaly, developmental abnormalities, visual impairment, hearing defects, and other severe neurological abnormalities in the fetus. In adults, infection has been associated with Guillain-Barré syndrome and other neurological disorders.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Zika Virus NS1 Control Antigen BA149R01?

The Zika Virus NS1 Control Antigen BA149R01 is primarily used for detection of IgA, IgG, and IgM antibodies in ELISA assays, specifically indirect and quantitative types.

How should the Zika Virus NS1 Control Antigen BA149R01 be stored to maintain its stability?

This antigen should be stored at -65°C and freeze/thaw cycles should be avoided. It is also recommended to sonicate the antigen before use to ensure proper solubilization.

Is the Zika Virus NS1 Control Antigen BA149R01 reactive with multiple species or specific to Zika Virus?

The antigen is species-reactive specifically with Zika Virus, targeting the Zika Virus NS1 protein.

What is the form and quantity provided for the Zika Virus NS1 Control Antigen BA149R01?

The product is supplied as a liquid form with a lot-specific concentration and is available in a 1 mg size.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.