Rhesus macaque LILRB1/CD85j/ILT2 Protein 4291

$270.00 – $900.00

Summary

Expression: HEK293
Binding assay: Yes (SPR)
Amino Acid Range: Ser17-His456

available size

Clear

SKU: 4291parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	F7H3G7
express system	HEK293
product tag	C-hFc
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.
molecular weight	The protein has a predicted MW of 74.5 kDa. Due to glycosylation, the protein migrates to 80-90 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Rhesus macaque LILRB1/CD85j/ILT2 Protein 4291

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.
Protein names Ig-like domain-containing protein
Gene names LILRB1,LILRB1
Mass 9544Da
Target Relevance information above includes information from UniProt accession: F7H3G7
The UniProt Consortium

Data

SPR with Rhesus macaque LILRB1/CD85j/ILT2 Protein

Anti-LILRB1 Antibody immobilized on CM5 Chip can bind Rhesus macaque LILRB1, hFc Tag with an affinity constant of 51.44 nM as determined in SPR assay (Biacore T200).

HPLC of Rhesus macaque LILRB1/CD85j/ILT2 Protein

The purity of Rhesus macaque LILRB1 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Rhesus macaque LILRB1/CD85j/ILT2 Protein

Rhesus macaque LILRB1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.