Rhesus macaque Latent TGF beta 1/TGFB1 Protein 4714

$405.00 – $1,350.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Leu30-Ser390(C33S)

SKU: 4714parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	F7HCV5
express system	HEK293
product tag	N-His
purity	> 95% as determined by Tris-Bis PAGE
background	Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.
molecular weight	The protein has a predicted MW of 31.4/12.8 kDa. Due to glycosylation, the protein migrates to 40-50/14-15 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Rhesus macaque Latent TGF beta 1/TGFB1 Protein 4714
protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Latent TGF beta 1Â cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 249 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF- beta 1. Disulfide-linked homodimers of LAP and TGF- beta 1 remain non-covalently associated after secretion, forming the small latent TGF- beta 1 complex.
Protein names
Transforming growth factor beta
Gene names
TGFB1,TGFB1
Protein family
TGF-beta family
Mass
9544Da
Function
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Subellular location
Secreted, extracellular space, extracellular matrix .
Structure
Homodimer; disulfide-linked.
Target Relevance information above includes information from UniProt accession: F7HCV5
The UniProt Consortium

ELISA with Rhesus macaque Latent TGF beta 1/TGFB1 Protein

Immobilized Rhesus macaque Latent TGF beta 1, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, His Tag with the EC50 of 0.74µg/ml determined by ELISA.

SDS-PAGE gel of Rhesus macaque Latent TGF beta 1/TGFB1 Protein

Rhesus macaque Latent TGF beta 1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.