Rat PLAU/uPA Protein 2339

$315.00 – $1,050.00

Summary

Expression: HEK293
Binding assay: Yes (SPR)
Amino Acid Range: Gly20-Phe432

SKU: 2339parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	NP_037217.3
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
background	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
molecular weight	The protein has a predicted MW of 46.91 kDa. The protein migrates to 30-35 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Rat PLAU/uPA Protein 2339

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Protein names Urokinase-type plasminogen activator (EC 3.4.21.73)
Gene names PLAU,PLAU
Mass 9541Da
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Target Relevance information above includes information from UniProt accession: A0A2K5WND1
The UniProt Consortium

Data

Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind Rat PLAU, His Tag with an affinity constant of 4.31 µM as determined in SPR assay (Biacore T200).

The purity of Rat PLAU is greater than 90% as determined by SEC-HPLC.

Rat PLAU on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.