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Human Complement Component C2 Protein 3687

$345.00$1,150.00

Summary

  • Expression: HEK293
  • Active: Yes (catalytic)
  • Amino Acid Range: Ala21-Leu752
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P06681

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.

molecular weight

The protein has a predicted MW of 82.2 kDa (Pro form). Due to glycosylation, the protein migrates to 83-90 kDa (Pro form) based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Complement Component C2 Protein 3687

Data

Activity assay with Human Complement Component C2 Protein
Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is >100 pmol/min/µg.
HPLC of Human Complement Component C2 Protein
The purity of Human Complement Component C2 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human Complement Component C2 Protein
Human Complement Component C2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product

Documents

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