PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer 2481

$1,150.00 – $4,250.00

Summary

Mammalian expression: HEK293
Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGAVGVGK peptide

available size

Clear

SKU: 2481parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	AAV53343(HLA-A*11:01)&P61769(B2M)&VVVGAVGVGK
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
molecular weight	tbd
available size	100 µg, 500 µg
endotoxin	Less than 1 EU per μg by the LAL method.

2481

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Protein names HLA class I histocompatibility antigen A alpha chain (MHC class I antigen)
Gene names HLA-A,HLA-A
Protein family MHC class I family
Mass 40937Da
Subellular location SUBCELLULAR LOCATION: Cell membrane {ECO:0000256\|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256\|ARBA:ARBA00004162}. Membrane {ECO:0000256\|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256\|ARBA:ARBA00004479}.
Target Relevance information above includes information from UniProt accession: Q5S3G3
The UniProt Consortium

Data

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Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.