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Mouse VCAM-1/CD106 Protein 2435

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Active: Yes (cell based assay)
  • Amino Acid Range: Phe25-Glu698
SKU: 2435parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

NP_035823.3

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.

molecular weight

The protein has a predicted MW of 75.48 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse VCAM-1/CD106 Protein 2435

Data

Cell based assay with Mouse VCAM-1/CD106 Protein
Measured by the ability of the immobilized protein to support adhesion of U937 human histiocytic lymphoma cells. When 5 x 104 cells/well are added to Mouse VCAM-1 coated plates (10 µg/ml with 100 µl/Well) , approximately 70 % - 80 % cells will adhere after 1 hour incubation at room temperature.
HPLC of Mouse VCAM-1/CD106 Protein
The purity of Mouse VCAM-1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse VCAM-1/CD106 Protein
Mouse VCAM-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product

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