Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q08423 |
express system | HEK293 |
product tag | C-hFc |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. |
molecular weight | The protein has a predicted MW of 34 kDa. Due to glycosylation, the protein migrates to 38-42 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse TFF1 Protein 3902
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gln22-Phe87
Mouse TFF1 Protein 3902
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. |
Protein names Trefoil factor 1 (Protein pS2) |
Gene names Tff1,Tff1 Bcei Ps2 |
Mass 10090Da |
Function Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. |
Subellular location Secreted. |
Tissues Strong expression found in normal gastric mucosa. Not detected in the small or large intestine nor in normal mammary gland. |
Target Relevance information above includes information from UniProt accession: Q08423 |
The UniProt Consortium |
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The purity of Mouse TFF1 is greater than 95% as determined by SEC-HPLC. |
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Mouse TFF1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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