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Mouse PVRIG Protein 3133

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ser35-Asp165
SKU: 3133parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A1B0GS01

express system

HEK293

product tag

C-hFc-Avi

purity

> 95% as determined by Tris-Bis PAGE

background

Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.

molecular weight

The protein has a predicted MW of 42.70 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse PVRIG Protein 3133

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.
Protein names
Poliovirus receptor related immunoglobulin domain containing
Gene names
Pvrig,Pvrig
Mass
10090Da
Target Relevance information above includes information from UniProt accession: A0A1B0GS01
The UniProt Consortium

Data

ELISA with Mouse PVRIG Protein
Immobilized Mouse Nectin-2, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.81ug/ml determined by ELISA.
SDS-PAGE gel of Mouse PVRIG Protein
Mouse PVRIG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product

Documents

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