Mouse PGK1 Protein 2395

$300.00 – $1,000.00

Summary

Expression: Baculovirus-Insect Cells
Pure: Yes (SDS-PAGE)
Amino Acid Range: Met1-Val417

SKU: 2395parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P09411
express system	Baculovirus-Insect Cells
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE
background	Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates.
molecular weight	The protein has a predicted MW of 46.07 kDa same as Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse PGK1 Protein 2395

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates.
Protein names
Phosphoglycerate kinase 1 (EC 2.7.2.3)
Gene names
Pgk1,Pgk1 Pgk-1
Protein family
Phosphoglycerate kinase family
Mass
10090Da
Function
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility.
Catalytic activity
BINDING 24..26; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 39; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 63..66; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 123; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 171; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 220; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 313; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 344; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 373..376; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"
Pathway
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
Subellular location
Cytoplasm .
Tissues
Testis, lung, brain, skeletal muscle, liver, intestine, and kidney (at protein level).
Structure
Monomer.
Target Relevance information above includes information from UniProt accession: P09411
The UniProt Consortium

Data

Mouse PGK1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.