Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | P47741 |
express system | HEK293 |
product tag | C-His-Avi |
purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
background | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
molecular weight | The protein has a predicted MW of 24.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per ug by the LAL method. |
Mouse OX40/TNFRSF4/CD134 Protein 3397
$210.00 – $700.00
Summary
- Expression: HEK293
- Functional: Yes (ELISA)
- Amino Acid Range: Val20-Pro211
Mouse OX40/TNFRSF4/CD134 Protein 3397
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
Protein names Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134) |
Gene names Tnfrsf4,Tnfrsf4 Ox40 Txgp1 |
Mass 10090Da |
Function Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity). |
Subellular location Membrane; Single-pass type I membrane protein. |
Tissues Expressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level). |
Structure Interacts with TRAF2, TRAF3 and TRAF5. |
Target Relevance information above includes information from UniProt accession: P47741 |
The UniProt Consortium |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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Documents
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