Mouse MOG/Myelin Oligodendrocyte Glycoprotein Protein 2535

$315.00 – $1,050.00

Summary

Expression: HEK293
Pure: Yes (SDS-PAGE)
Amino Acid Range: Gly29-Thr156

SKU: 2535parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q61885
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE
background	Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM).
molecular weight	The protein has a predicted MW of 15.68 kDa. Due to glycosylation, the protein migrates to 18-25 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse MOG/Myelin Oligodendrocyte Glycoprotein Protein 2535

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM).
Protein names Myelin-oligodendrocyte glycoprotein
Gene names Mog,Mog
Protein family Immunoglobulin superfamily, BTN/MOG family
Mass 10090Da
Function Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.
Subellular location Membrane; Multi-pass membrane protein.
Tissues Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. Reduced expression levels are observed in jimpy and quacking dysmyelinating mutant mice.
Structure Homodimer.
Target Relevance information above includes information from UniProt accession: Q61885
The UniProt Consortium

SDS-PAGE gel of Mouse MOG/Myelin Oligodendrocyte Glycoprotein Protein

Mouse MOG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.