Mouse LRRC15/LIB Protein 3116

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Tyr22-Gly536

SKU: 3116parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q80X72
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
background	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.
molecular weight	The protein has a predicted MW of 58.56 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1 EU per μg by the LAL method.

Mouse LRRC15/LIB Protein 3116

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.Â LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.
Protein names Leucine-rich repeat-containing protein 15
Gene names Lrrc15,Lrrc15
Mass 10090Da
Subellular location Cell membrane ; Single-pass type I membrane protein .
Tissues Expressed in chodrocytes (at protein level).
Target Relevance information above includes information from UniProt accession: Q80X72
The UniProt Consortium

Immobilized Anti-LRRC15 Antibody, hFc Tag at 1 µg/ml (100 µl/Well) on the plate. Dose response curve for Mouse LRRC15, His Tag with the EC50 of 11.7 ng/ml determined by ELISA.

The purity of Mouse LRRC15 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse LRRC15/LIB Protein

Mouse LRRC15 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.