Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q80X72 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
background | The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
molecular weight | The protein has a predicted MW of 58.56 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1 EU per μg by the LAL method. |
Mouse LRRC15/LIB Protein 3116
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Functional: Yes (ELISA)
- Amino Acid Range: Tyr22-Gly536
Mouse LRRC15/LIB Protein 3116
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
Protein names Leucine-rich repeat-containing protein 15 |
Gene names Lrrc15,Lrrc15 |
Mass 10090Da |
Subellular location Cell membrane ; Single-pass type I membrane protein . |
Tissues Expressed in chodrocytes (at protein level). |
Target Relevance information above includes information from UniProt accession: Q80X72 |
The UniProt Consortium |
Publications
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We haven't added any publications to our database yet. |
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