Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q6PHB0 |
express system | HEK293 |
product tag | C-hFc |
purity | > 95% as determined by Tris-Bis PAGE |
background | IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA. |
molecular weight | The protein has a predicted MW of 52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse IL-20RA Protein 3729
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Binding assay: Yes (SPR)
- Amino Acid Range: Val33-Lys253
Mouse IL-20RA Protein 3729
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA. |
Protein names Interleukin-20 receptor subunit alpha (IL-20 receptor subunit alpha) (IL-20R-alpha) (IL-20RA) (IL-20R1) |
Gene names Il20ra,Il20ra |
Protein family Type II cytokine receptor family |
Mass 10090Da |
Function The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26 (By similarity). |
Subellular location Membrane ; Single-pass type I membrane protein . |
Structure Heterodimer with IL20RB and heterodimer with IL10RB. |
Target Relevance information above includes information from UniProt accession: Q6PHB0 |
The UniProt Consortium |
Publications
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We haven't added any publications to our database yet. |
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