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Mouse HGFA Protein (pro form) 3911

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gln35-Ser653
SKU: 3911parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9R098

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON.

molecular weight

The protein has a predicted MW of 67.9 kDa. Due to glycosylation, the protein (pro form) migrates to 80-100 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse HGFA Protein (pro form) 3911

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON.
Protein names
Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain]
Gene names
Hgfac,Hgfac
Protein family
Peptidase S1 family
Mass
10090Da
Function
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
Subellular location
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Structure
Heterodimer of a short chain and a long chain linked by a disulfide bond.
Target Relevance information above includes information from UniProt accession: Q9R098
The UniProt Consortium

HPLC of Mouse HGFA Protein (pro form)
The purity of Mouse HGFA (pro form) is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse HGFA Protein (pro form)
Mouse HGFA (pro form) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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