Mouse FSH alpha&beta Protein 2017

$315.00 – $1,050.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Leu25-Ser120 (FSH alpha) & His20-Glu130 (FSH beta)

SKU: 2017parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P01216(FSH alpha)&Q60687(FSH beta)
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	FSH (Follicle-stimulating hormone) is a gonadotropin, a glycoprotein polypeptide hormone. It has a functionally indispensable 96 amino acid α subunit that is common to LH, TSH and hCG, in addition to a structurally unique β subunit. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
molecular weight	The protein has a predicted MW of 12.28 kDa (FSH alpha) and 13.67 kDa (FSH beta). Due to glycosylation, the protein migrates to 26-36 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse FSH alpha&beta Protein 2017

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
FSH (Follicle-stimulating hormone) is a gonadotropin, a glycoprotein polypeptide hormone. It has a functionally indispensable 96 amino acid α subunit that is common to LH, TSH and hCG, in addition to a structurally unique β subunit. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
Protein names Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain)
Gene names Cga,Cga
Protein family Glycoprotein hormones subunit alpha family
Mass 13565Da
Function Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Subellular location Secreted .
Structure Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
Target Relevance information above includes information from UniProt accession: P01216
The UniProt Consortium

Data

The purity of Mouse FSH alpha&beta is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse FSH alpha&beta Protein

Mouse FSH alpha&beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.