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Mouse FLT3 Ligand Protein 2614

$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gly27-Gln189
SKU: 2614parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P49772

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

molecular weight

The protein has a predicted MW of 19.61 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse FLT3 Ligand Protein 2614

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Flt-3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Protein names
Fms-related tyrosine kinase 3 ligand (Flt3 ligand) (Flt3L) (SL cytokine)
Gene names
Flt3lg,Flt3lg Flt3l
Mass
10090Da
Function
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Subellular location
Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted. Note=Biologically active.; [Isoform 4]: Secreted. Note=Inactive.
Structure
Homodimer (soluble isoform).
Target Relevance information above includes information from UniProt accession: P49772
The UniProt Consortium

SPR with Mouse FLT3 Ligand Protein
Mouse FLT3 Ligand, His Tag captured on CM5 Chip via anti-his antibody can bind Human FLT3, hFc Tag with an affinity constant of 0.18 nM as determined in SPR assay (Biacore T200).
ELISA with Mouse FLT3 Ligand Protein
Immobilized Mouse FLT3 Ligand, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human FLT3, hFc Tag with the EC50 of 39.3ng/ml determined by ELISA (QC Test).
HPLC of Mouse FLT3 Ligand Protein
The purity of Mouse FLT3 Ligand is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse FLT3 Ligand Protein
Mouse FLT3 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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