Mouse EVA-1/MPZL2 Protein 2998

$300.00 – $1,000.00

Summary

Expression: HEK293
Pure: Yes (SDS-PAGE)
Amino Acid Range: Val27-Leu154

SKU: 2998parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	O70255
express system	HEK293
product tag	C-hFc
purity	> 95% as determined by Tris-Bis PAGE
background	MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons.
molecular weight	The protein has a predicted MW of 41.42 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse EVA-1/MPZL2 Protein 2998

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons.
Protein names Myelin protein zero-like protein 2 (Epithelial V-like antigen 1)
Gene names Mpzl2,Mpzl2 Eva Eva1
Protein family Myelin P0 protein family
Mass 10090Da
Function Mediates homophilic cell-cell adhesion.
Subellular location Membrane ; Single-pass type I membrane protein .
Tissues Widely expressed (PubMed:29982980, PubMed:9585423). Expressed in the cochlea, in Deiters' cells, possibly at contact sites with the basilar membrane (PubMed:29961571, PubMed:29982980). Expressed in both outer and inner auditory hair cells (PubMed:29961571, PubMed:29982980). In the stria vascularis, detected in the basal cell layer (PubMed:29961571). Not detected in thymocytes, lymphocytes, macrophage or dendritic cells (PubMed:9585423).
Target Relevance information above includes information from UniProt accession: O70255
The UniProt Consortium

SDS-PAGE gel of Mouse EVA-1/MPZL2 Protein

Mouse EVA-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.