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Mouse EVA-1/MPZL2 Protein 2998

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Pure: Yes (SDS-PAGE)
  • Amino Acid Range: Val27-Leu154
SKU: 2998parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

O70255

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE

background

MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons.

molecular weight

The protein has a predicted MW of 41.42 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse EVA-1/MPZL2 Protein 2998

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons.
Protein names
Myelin protein zero-like protein 2 (Epithelial V-like antigen 1)
Gene names
Mpzl2,Mpzl2 Eva Eva1
Protein family
Myelin P0 protein family
Mass
10090Da
Function
Mediates homophilic cell-cell adhesion.
Subellular location
Membrane ; Single-pass type I membrane protein .
Tissues
Widely expressed (PubMed:29982980, PubMed:9585423). Expressed in the cochlea, in Deiters' cells, possibly at contact sites with the basilar membrane (PubMed:29961571, PubMed:29982980). Expressed in both outer and inner auditory hair cells (PubMed:29961571, PubMed:29982980). In the stria vascularis, detected in the basal cell layer (PubMed:29961571). Not detected in thymocytes, lymphocytes, macrophage or dendritic cells (PubMed:9585423).
Target Relevance information above includes information from UniProt accession: O70255
The UniProt Consortium

SDS-PAGE gel of Mouse EVA-1/MPZL2 Protein
Mouse EVA-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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