Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | O35215 |
express system | E.coli |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. |
molecular weight | The protein has a predicted MW of 14.31 kDa same as Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse DDT Protein 3300
$270.00 – $900.00
Summary
- Expression: E.coli
- Pure: Yes (HPLC)
- Amino Acid Range: Pro2-Leu118
Mouse DDT Protein 3300
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. |
Protein names D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase) |
Gene names Ddt,Ddt |
Protein family MIF family |
Mass 13077Da |
Function FUNCTION: Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). {ECO:0000250|UniProtKB:P30046}. |
Catalytic activity CATALYTIC ACTIVITY: Reaction=D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2; Xref=Rhea:RHEA:18441, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:27404, ChEBI:CHEBI:58782; EC=4.1.1.84; Evidence={ECO:0000250|UniProtKB:P30046}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18442; Evidence={ECO:0000250|UniProtKB:P30046}; |
Subellular location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P30046}. |
Structure SUBUNIT: Homotrimer. {ECO:0000250|UniProtKB:P30046}. |
Target Relevance information above includes information from UniProt accession: O35215 |
The UniProt Consortium |
Data
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The purity of Mouse DDT is greater than 95% as determined by SEC-HPLC. |
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Mouse DDT on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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Protocols
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