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Mouse CLEC-1 Protein 3663

$270.00$900.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gln73-Gln269
SKU: 3663parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

Q8BWY2

express system

HEK293

product tag

N-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.

molecular weight

The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse CLEC-1 Protein 3663

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
Protein names
C-type lectin domain family 1 member A
Gene names
Clec1a,Clec1a
Mass
10090Da
Subellular location
Membrane ; Single-pass type II membrane protein .
Target Relevance information above includes information from UniProt accession: Q8BWY2
The UniProt Consortium

Data

HPLC of Mouse CLEC-1 Protein
The purity of Mouse CLEC-1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse CLEC-1 Protein
Mouse CLEC-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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