Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q8BWY2 |
express system | HEK293 |
product tag | N-hFc |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis. |
molecular weight | The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse CLEC-1 Protein 3663
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gln73-Gln269
Mouse CLEC-1 Protein 3663
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis. |
Protein names C-type lectin domain family 1 member A |
Gene names Clec1a,Clec1a |
Mass 10090Da |
Subellular location Membrane ; Single-pass type II membrane protein . |
Target Relevance information above includes information from UniProt accession: Q8BWY2 |
The UniProt Consortium |
Data
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The purity of Mouse CLEC-1 is greater than 95% as determined by SEC-HPLC. |
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Mouse CLEC-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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We haven't added any publications to our database yet. |
Protocols
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