Mouse CD228/MFI2 Protein 3215

$270.00 – $900.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Val20-Cys709

SKU: 3215parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q9R0R1
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Melanotransferrin (MTf) or melanoma tumor antigen p97 is a transferrin (Tf) homolog that is found predominantly bound to the cell membrane via a glycosyl phosphatidylinositol anchor. The molecule is a member of the Tf superfamily and binds iron through a single high-affinity iron(III)-binding site.
molecular weight	The protein has a predicted MW of 77.30 kDa. Due to glycosylation, the protein migrates to 78-80 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse CD228/MFI2 Protein 3215

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Melanotransferrin (MTf) or melanoma tumor antigen p97 is a transferrin (Tf) homolog that is found predominantly bound to the cell membrane via a glycosyl phosphatidylinositol anchor. The molecule is a member of the Tf superfamily and binds iron through a single high-affinity iron(III)-binding site.
Protein names
Melanotransferrin (Membrane-bound transferrin-like protein p97) (MTf) (CD antigen CD228)
Gene names
Meltf,Meltf Mfi2 Mtf
Protein family
Transferrin family
Mass
10090Da
Function
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Catalytic activity
BINDING 78; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 107; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 132; /ligand="hydrogencarbonate"; /ligand_id="ChEBI:CHEBI:17544"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 136; /ligand="hydrogencarbonate"; /ligand_id="ChEBI:CHEBI:17544"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 138; /ligand="hydrogencarbonate"; /ligand_id="ChEBI:CHEBI:17544"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 139; /ligand="hydrogencarbonate"; /ligand_id="ChEBI:CHEBI:17544"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 210; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 279; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 451; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="2"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 556; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="2"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"; BINDING 625; /ligand="Fe(3+)"; /ligand_id="ChEBI:CHEBI:29034"; /ligand_label="2"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00741"
Subellular location
Cell membrane ; Lipid-anchor, GPI-anchor .
Target Relevance information above includes information from UniProt accession: Q9R0R1
The UniProt Consortium

Data

The purity of Mouse CD228 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse CD228/MFI2 Protein

Mouse CD228 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.